Rajan V, Varghese B, van Leeuwen T G, Steenbergen W
Biomedical Technology Institute, Biophysical Engineering Group, University of Twente, P.O. Box 217, NL-7500AE Enschede, The Netherlands.
Opt Lett. 2006 Feb 15;31(4):468-70. doi: 10.1364/ol.31.000468.
We report on the quantitative influence of speckles in laser Doppler perfusion imaging. The influence of speckles on the signal amplitude and on the Doppler spectrum is demonstrated experimentally for particle suspensions with different scattering levels and various beam widths. It is shown that the type of tissue affects the instrumental response through the effect of lateral light diffusion on the number of speckles involved in the detection process. These effects are largest for narrow beams.
我们报告了激光多普勒灌注成像中散斑的定量影响。针对具有不同散射水平和各种光束宽度的颗粒悬浮液，通过实验证明了散斑对信号幅度和多普勒频谱的影响。结果表明，组织类型通过横向光扩散对检测过程中涉及的散斑数量的影响来影响仪器响应。对于窄光束，这些影响最为显著。
