Vejerslev L O, Larsen G, Jacobsen M
Department of Medical Genetics, John F. Kennedy Institute, Glostrup/Copenhagen, Denmark.
Eur J Obstet Gynecol Reprod Biol. 1991 Jun 5;40(1):73-7. doi: 10.1016/0028-2243(91)90048-p.
A case of partial hydatidiform mole revealed by genetic marker analysis one maternal and two paternal chromosome complements. Levels of serum human chorionic gonadotropin were persistently elevated during follow-up. Avillous curettage specimens prior to chemotherapy were morphologically suspicious for gestational choriocarcinoma. It is still uncertain whether the risk for gestational choriocarcinoma preceded by partial mole exceeds the risk related to non-molar abortions. Careful follow-up with serial serum human chorionic gonadotropin levels is required to detect persistent disease.
一例部分性葡萄胎经基因标记分析显示有一个母系染色体补体和两个父系染色体补体。随访期间血清人绒毛膜促性腺激素水平持续升高。化疗前的无绒毛刮宫标本在形态学上怀疑为妊娠性绒毛膜癌。部分性葡萄胎继发妊娠性绒毛膜癌的风险是否超过与非葡萄胎流产相关的风险仍不确定。需要通过连续检测血清人绒毛膜促性腺激素水平进行仔细随访以发现持续性疾病。