Maruya Jun, Seki Yasuhiro, Morita Kenichi, Nishimaki Keiichi, Minakawa Takashi
Department of Neurosurgery, Akita Red Cross Hospital, Japan.
Neurol Med Chir (Tokyo). 2006 Feb;46(2):92-7. doi: 10.2176/nmc.46.92.
Meningeal hemangiopericytoma is rare, and only seven cases have manifested as intracranial hemorrhage. We treated two patients with meningeal hemangiopericytoma manifesting as life-threatening massive intracerebral hemorrhage. Case 1: A 66-year-old woman presented with consciousness disturbance and left hemiparesis. Computed tomography showed a mass lesion in the right frontal parasagittal region and massive hematoma in the brain tissue at the medial border of the lesion. Immediate evacuation of the hematoma was performed. Postoperative magnetic resonance imaging revealed a well-enhanced mass lesion with small intratumoral hemorrhage. The tumor was removed totally through a bilateral frontal craniotomy. The postoperative course was uneventful. The histological diagnosis was meningeal hemangiopericytoma. Radiotherapy was not performed. Case 2: A 59-year-old man presented with consciousness disturbance. Computed tomography showed a mass lesion in the right frontotemporal convexity region and massive hematoma in the brain tissue at the medial border of the lesion. His neurological condition was refractory to any treatment and the clinical diagnosis of brain death was confirmed. Autopsy was performed and the histological diagnosis was meningeal hemangiopericytoma. Meningeal hemangiopericytoma manifesting as intracranial hemorrhage is quite rare, but carries the risk of life-threatening massive bleeding from the tumor.
脑膜血管外皮细胞瘤较为罕见,仅有7例表现为颅内出血。我们治疗了2例表现为危及生命的大量脑出血的脑膜血管外皮细胞瘤患者。病例1:一名66岁女性,出现意识障碍和左侧偏瘫。计算机断层扫描显示右侧额旁矢状区有一肿块病变,病变内侧缘脑组织内有大量血肿。立即进行了血肿清除术。术后磁共振成像显示有一个强化良好的肿块病变,肿瘤内有小出血灶。通过双侧额部开颅术将肿瘤完全切除。术后过程顺利。组织学诊断为脑膜血管外皮细胞瘤。未进行放疗。病例2:一名59岁男性,出现意识障碍。计算机断层扫描显示右侧额颞叶凸面区有一肿块病变,病变内侧缘脑组织内有大量血肿。他的神经状况对任何治疗均无反应,临床确诊为脑死亡。进行了尸检,组织学诊断为脑膜血管外皮细胞瘤。表现为颅内出血的脑膜血管外皮细胞瘤非常罕见,但存在肿瘤危及生命的大量出血风险。