Mac Tu Luong, Le Van Tuan, Vu Anh Nhi, Preux Pierre-Marie, Ratsimbazafy Voa
Institute of Neuroepidemiology and Tropical Neurology (EA3174), School of Medicine, 2 rue du Docteur Marcland, 87025 Limoges Cedex, France.
Epilepsia. 2006 Feb;47(2):330-4. doi: 10.1111/j.1528-1167.2006.00425.x.
In developing countries, from 80 to 90% of the people with active epilepsy do not have access to treatment. A multitude of factors such as nonavailability of antiepileptic drugs (AEDs) contributes to the treatment gap in epilepsy. Our study carried out in 2003 in southern Vietnam showed that 57% of pharmacies had AEDs. A majority of these pharmacies were located in specific areas like market area or hospital area. The pharmacist in charge was present in only 24% of the pharmacies. The different kinds of AEDs available were carbamazepine (94%), phenytoin (61%), valproate (56%) and diazepam (16%). The maximum stock of a drug was two box. The availability of AEDs in southern Vietnam can be regarded as sufficient but does not allow an adequate treatment for a long time. An effort must be made to sensitize professional health workers to decrease the treatment gap in epilepsy.
在发展中国家,80%至90%的活动性癫痫患者无法获得治疗。抗癫痫药物(AEDs)无法获取等诸多因素导致了癫痫治疗缺口。我们2003年在越南南部开展的研究表明,57%的药店有AEDs。这些药店大多位于特定区域,如市场区域或医院区域。仅有24%的药店有负责药剂师。可供使用的不同种类AEDs有卡马西平(94%)、苯妥英(61%)、丙戊酸盐(56%)和地西泮(16%)。一种药物的最大库存为两盒。越南南部AEDs的可获取情况可被视为充足,但无法长期提供充分治疗。必须努力提高专业卫生工作者的认识,以缩小癫痫治疗缺口。