Lind Britta, Eriksson Michael, Roumina Simin, Nowak Jacek, Brodin Lars-Ake
Department of Clinical Physiology, Karolinska University Hospital Huddinge, Stockholm, Sweden.
J Am Soc Echocardiogr. 2006 Mar;19(3):255-65. doi: 10.1016/j.echo.2005.10.012.
Rapid myocardial isovolumic motions are reportedly involved in the left ventricular reshaping process and may contribute to total systolic myocardial shortening. In this study, the qualitative and quantitative analysis of longitudinal myocardial isovolumic displacement was performed in 49 healthy individuals (23 men and 26 women) in age groups 21 to 49 and 50 to 76 years using tissue velocity echocardiography. The obtained isovolumic contraction and relaxation displacement curves were biphasic and displayed a significant regional heterogeneity most probably reflecting active presystolic and postsystolic reshaping of left ventricular cavity. Besides some sex difference in younger individuals, there was an age-dependent lengthening of the isovolumic relaxation time and their motion components. Even if being of short duration, the longitudinal myocardial isovolumic displacement may accounted for as much as 14% of the total longitudinal myocardial shortening, a fact which should be taken into consideration when assessing left ventricular systolic function.
据报道，快速心肌等容运动参与左心室重塑过程，并可能有助于总的收缩期心肌缩短。在本研究中，使用组织速度超声心动图对49名年龄在21至49岁以及50至76岁的健康个体（23名男性和26名女性）进行了纵向心肌等容位移的定性和定量分析。获得的等容收缩和舒张位移曲线呈双相，并且显示出明显的区域异质性，这很可能反映了左心室腔在收缩前期和收缩后期的主动重塑。除了年轻个体中存在一些性别差异外，等容舒张时间及其运动成分存在年龄依赖性延长。即使持续时间较短，纵向心肌等容位移可能占总的纵向心肌缩短的14%，在评估左心室收缩功能时应考虑这一事实。
