Harle Deacon E, Evans Bruce J W
The Neville Chappell Research Clinic, The Institute of Optometry, London, UK.
Optom Vis Sci. 2006 Feb;83(2):82-7. doi: 10.1097/01.opx.0000200680.95968.3e.
A literature review reveals historical references to an association between migraine headache and refractive errors, but a lack of scientific evidence relating to these claims.
In a masked case-controlled study, we investigated the four aspects of refractive errors that have been implicated in the literature as correlated with migraine: spherical refractive error, astigmatic refractive error, anisometropia, and uncorrected ametropia. We also compared the calculated scalar value of refractive error, aided and unaided visual acuity, and spectacle use in migraine and control groups. We then investigated the relationship between refractive components and key migraine headache variables.
Compared with the control group, the migraine group had higher degrees of astigmatic components of refractive error assessed both objectively (C, p = 0.01; C(0), p = 0.01; C(45), p = 0.05) and subjectively (C, p = 0.03; C(0), p = 0.03; C(45), p = 0.05), uncorrected astigmatic components of refractive error (C(0), p = 0.02; C(45), p = 0.04), and anisometropia (p = 0.06).
Perhaps the historical literature is indeed correct that low degrees of astigmatism and anisometropia are relevant in migraine. Our most significant finding was of higher degrees of astigmatism in the migraine group. This study does indicate that people who experience migraine headaches should attend their optometrist regularly to ensure that their refractive errors are appropriately corrected.
文献综述揭示了偏头痛与屈光不正之间关联的历史记载，但缺乏与这些说法相关的科学证据。
在一项双盲病例对照研究中，我们调查了文献中认为与偏头痛相关的屈光不正的四个方面：球镜屈光不正、散光屈光不正、屈光参差和未矫正的屈光不正。我们还比较了偏头痛组和对照组屈光不正的计算标量值、矫正和未矫正视力以及眼镜使用情况。然后我们研究了屈光成分与偏头痛关键变量之间的关系。
与对照组相比，偏头痛组在客观（C，p = 0.01；C(0)，p = 0.01；C(45)，p = 0.05）和主观（C，p = 0.03；C(0)，p = 0.03；C(45)，p = 0.05）评估中散光屈光成分度数更高，未矫正的散光屈光成分（C(0)，p = 0.02；C(45)，p = 0.04）以及屈光参差（p = 0.06）也更高。
也许历史文献确实是正确的，即低度散光和屈光参差与偏头痛有关。我们最显著的发现是偏头痛组散光度数更高。这项研究确实表明，经历偏头痛的人应该定期去看验光师，以确保他们的屈光不正得到适当矫正。
