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心脏病中干细胞递送的方法。

Methods of stem cell delivery in cardiac diseases.

作者信息

Perin Emerson C, López Javier

机构信息

Department of Adult Cardiology, Texas Heart Institute at St Luke's Episcopal Hospital, Houston, TX 77030, USA.

出版信息

Nat Clin Pract Cardiovasc Med. 2006 Mar;3 Suppl 1:S110-3. doi: 10.1038/ncpcardio0447.

DOI:10.1038/ncpcardio0447
PMID:16501616
Abstract

There are several strategies for cell delivery in cardiac stem cell therapy. The cells can be delivered through coronary arteries, coronary veins, or peripheral veins. Alternatively, direct intramyocardial injection can be performed, using a surgical, transendocardial, or transvenous approach. In this article, we describe the most important conceptual aspects and the evidence for the use of these techniques, with emphasis on intramyocardial injections.

摘要

在心脏干细胞治疗中,有几种细胞递送策略。细胞可以通过冠状动脉、冠状静脉或外周静脉进行递送。或者,可采用外科手术、经心内膜或经静脉途径进行直接心肌内注射。在本文中,我们描述了这些技术应用的最重要概念方面及证据,重点是心肌内注射。

相似文献

1
Methods of stem cell delivery in cardiac diseases.心脏病中干细胞递送的方法。
Nat Clin Pract Cardiovasc Med. 2006 Mar;3 Suppl 1:S110-3. doi: 10.1038/ncpcardio0447.
2
Cellular cardiomyoplasty by catheter-based infusion of stem cells in clinical settings.临床环境中通过导管输注干细胞进行细胞心肌成形术。
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[Transcatheter cell therapy of heart failure: state of the art].[心力衰竭的经导管细胞治疗:现状]
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Tracking cardiac engraftment and distribution of implanted bone marrow cells: Comparing intra-aortic, intravenous, and intramyocardial delivery.追踪植入骨髓细胞的心脏植入及分布:比较主动脉内、静脉内和心肌内注射途径
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Is stem cell therapy ready for patients? Stem Cell Therapy for Cardiac Repair. Ready for the Next Step .干细胞疗法对患者来说准备好了吗?用于心脏修复的干细胞疗法。准备好迈向下一步了。
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Trans-coronary transplantation may be an optimal route in cellular cardiomyoplasty with stem cells.经冠状动脉移植可能是干细胞心肌成形术中的最佳途径。
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Resident progenitors and bone marrow stem cells in myocardial renewal and repair.心肌更新与修复中的常驻祖细胞和骨髓干细胞。
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引用本文的文献

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Stem Cell Therapy for Myocardial Infarction Recovery: Advances, Challenges, and Future Directions.用于心肌梗死恢复的干细胞疗法:进展、挑战与未来方向
Biomedicines. 2025 May 16;13(5):1209. doi: 10.3390/biomedicines13051209.
2
Regenerative Medicine and Nanotechnology Approaches against Cardiovascular Diseases: Recent Advances and Future Prospective.对抗心血管疾病的再生医学与纳米技术方法:最新进展与未来展望
Curr Stem Cell Res Ther. 2025;20(1):50-71. doi: 10.2174/011574888X263530230921074827.
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Adipose Stem Cell-Seeded Decellularized Porcine Pericardium: A Promising Functional Biomaterial to Synergistically Restore the Cardiac Functions Post-Myocardial Infarction.
脂肪干细胞接种的去细胞猪心包:一种有望协同恢复心肌梗死后心脏功能的功能性生物材料。
Vet Sci. 2023 Nov 17;10(11):660. doi: 10.3390/vetsci10110660.
4
Therapeutic application of regeneration-associated cells: a novel source of regenerative medicine.再生相关细胞的治疗应用:再生医学的新来源。
Stem Cell Res Ther. 2023 Aug 2;14(1):191. doi: 10.1186/s13287-023-03428-y.
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Novel Techniques to Improve Precise Cell Injection.提高精确细胞注射的新方法。
Int J Mol Sci. 2021 Jun 14;22(12):6367. doi: 10.3390/ijms22126367.
6
Three-dimensional scaffold-free microtissues engineered for cardiac repair.用于心脏修复的三维无支架微组织工程。
J Mater Chem B. 2020 Sep 14;8(34):7571-7590. doi: 10.1039/d0tb01528h. Epub 2020 Jul 29.
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Multi-walled carbon nanotubes induce oxidative stress, apoptosis, and dysfunction in isolated rat heart mitochondria: protective effect of naringin.多壁碳纳米管诱导分离大鼠心脏线粒体氧化应激、细胞凋亡和功能障碍:柚皮苷的保护作用。
Environ Sci Pollut Res Int. 2020 Apr;27(12):13447-13456. doi: 10.1007/s11356-020-07943-w. Epub 2020 Feb 5.
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Hydrogel vehicles for sequential delivery of protein drugs to promote vascular regeneration.水凝胶载体用于序贯递呈蛋白类药物促进血管再生。
Adv Drug Deliv Rev. 2019 Sep-Oct;149-150:95-106. doi: 10.1016/j.addr.2019.08.005. Epub 2019 Aug 14.
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A self-healing hydrogel as an injectable instructive carrier for cellular morphogenesis.一种自修复水凝胶作为可注射的指导细胞形态发生的载体。
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