特发性红细胞增多症患者中JAK2 V617F突变的发生率。
The incidence of the JAK2 V617F mutation in patients with idiopathic erythrocytosis.
作者信息
Percy Melanie J, Jones Frank G C, Green Anthony R, Reilly John T, McMullin Mary Frances
出版信息
Haematologica. 2006 Mar;91(3):413-4. Epub 2006 Feb 17.
PMID:16503548
Abstract
Sixty-three patients with erythrocytosis exhibiting a range of erythropoietin levels were screened for the JAK2 V617F mutation. One patient (1.6%) was found to have this mutation, and has remained stable for 9 years, suggesting that the JAK2 V617F mutation is rare in patients with idiopathic erythrocytosis.
摘要
对63例红细胞增多症患者进行了促红细胞生成素水平测定，并筛查了JAK2 V617F突变。发现1例患者（1.6%）存在该突变，且9年来病情一直稳定，提示JAK2 V617F突变在特发性红细胞增多症患者中较为罕见。
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