孤立性阴茎卡波西肉瘤：1例HIV阴性男性患者放疗成功治疗报告

Exclusive penile Kaposi's sarcoma: report of an HIV-negative man successfully treated with radiotherapy.

作者信息

Zargari O

机构信息

Department of Dermatology, Guilan University of Medical Sciences, Rasht, Iran.

出版信息

J Eur Acad Dermatol Venereol. 2006 Mar;20(3):318-20. doi: 10.1111/j.1468-3083.2006.01423.x.

DOI:10.1111/j.1468-3083.2006.01423.x

PMID:16503896

Abstract

Kaposi's sarcoma (KS) is a rare neoplasm of endovascular cells with multifocal origin. The exact nature of the disease is not clear, but current data support the notion that KS is a vascular hyperplasia with a tight link to human herpesvirus 8 (HHV-8) infection. Classic KS occurs primarily on the lower extremities in elderly men living in the Mediterranean region. Penile involvement has rarely been reported in non-human immune deficiency virus (HIV) patients. Herein we present a 71-year-old HIV-negative man with isolated KS on the penis who was treated successfully with radiotherapy. A review of the literature is also presented.

摘要

卡波西肉瘤（KS）是一种起源多灶的罕见血管内皮细胞肿瘤。该病的确切性质尚不清楚，但目前的数据支持KS是一种与人类疱疹病毒8型（HHV-8）感染密切相关的血管增生这一观点。经典型KS主要发生在地中海地区老年男性的下肢。在非人类免疫缺陷病毒（HIV）患者中，阴茎受累的情况鲜有报道。在此，我们报告一例71岁的HIV阴性男性，其阴茎单独发生KS，经放射治疗成功治愈。同时还对相关文献进行了综述。