癫痫与生殖障碍：促性腺激素释放激素网络的作用
Epilepsy and reproductive disorders: the role of the gonadotropin-releasing hormone network.
作者信息
Fawley Jessica A, Pouliot Wendy A, Dudek F Edward
机构信息
Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
出版信息
Epilepsy Behav. 2006 May;8(3):477-82. doi: 10.1016/j.yebeh.2006.01.019. Epub 2006 Feb 28.
Individuals with temporal lobe epilepsy have an increased incidence of reproductive dysfunction. The comorbidity may be due to the acute effects of the seizures, the chronic effects of the epilepsy, and/or the use of antiepileptic drugs on the gonadotropin-releasing hormone network and the hypothalamic-pituitary-gonadal axis. This review provides a brief overview of evidence from experimental animal and clinical studies exploring the basis for epilepsy-associated reproductive abnormalities.
颞叶癫痫患者生殖功能障碍的发生率增加。这种合并症可能归因于癫痫发作的急性影响、癫痫的慢性影响，和/或抗癫痫药物对促性腺激素释放激素网络及下丘脑-垂体-性腺轴的作用。这篇综述简要概述了来自实验动物和临床研究的证据，这些研究探索了癫痫相关生殖异常的基础。
Zotero 插件