抗病毒药物：呋喃基嘧啶酮的合成及其细胞生长抑制和抗病毒活性评估
Antiviral agents: synthesis of furylpyrimidinones and evaluation of their cytostatic and antiviral activity.
作者信息
Botta M, De Angelis F, Corelli F, Menichincheri M, Nicoletti R, Marongiu M E, Pani A, La Colla P
机构信息
Dipartimento Farmaco Chimico Tecnologico, Università di Siena.
出版信息
Arch Pharm (Weinheim). 1991 Apr;324(4):203-7. doi: 10.1002/ardp.19913240403.
PMID:1650546
Abstract
Condensation between furyllithium reagents and pyrimidinones 1, 2, 3, and 4 has been studied. The product composition is strongly dependent upon the reaction conditions and purification methodologies. Cytostatic and antiviral activities of some substrates and reaction products is reported.
摘要
已对呋锂试剂与嘧啶酮1、2、3和4之间的缩合反应进行了研究。产物组成强烈依赖于反应条件和纯化方法。报道了一些底物和反应产物的细胞抑制和抗病毒活性。
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