Weyermann M, Rothenbacher D, Brenner H
Department of Epidemiology, The German Centre for Research on Ageing, Heidelberg, Germany.
Int J Obes (Lond). 2006 Aug;30(8):1281-7. doi: 10.1038/sj.ijo.0803260. Epub 2006 Feb 28.
Whereas a recently published meta-analysis showed that ever breastfeeding reduces the risk of obesity in childhood significantly, the recent literature describing the relationship between duration of breastfeeding and risk of overweight or obesity in childhood remains inconclusive.
Between November 2000 and November 2001, all mothers and their newborns were recruited after delivery at the Department of Gynecology and Obstetrics at the University of Ulm, Germany. Active follow-up was performed at the age of 12 months and 24 months.
Of the 1066 children included in the baseline examination, information on body mass index was available for 855 (80%) at the 2-year follow-up. At this age 72 children (8.4%) were overweight and 24 (2.8%) were severely overweight. Whereas 76 children (8.9%) were never breastfed, 533 children (62.3%) were breastfed for at least 6 months, and 322 children (37.7%) were exclusively breastfed for at least 6 months. Compared to children who were breastfed for less than 3 months, the adjusted odds ratio (OR) for overweight was 0.4 (95% confidence interval (CI) 0.2-0.8) in children who were breastfed for at least 6 months. When considering the time of exclusive breastfeeding, the adjusted OR for overweight was 0.8 (95% CI 0.4; 1.5) in children who were exclusively breastfed for at least 3 but less than 6 months and 0.4 (95% CI 0.2; 0.9) in children who were exclusively breastfed for at least 6 months compared to children who were exclusively breastfed less than 3 months.
These results highlight the importance of prolonged breastfeeding for the prevention of overweight in children.
尽管最近发表的一项荟萃分析表明，曾经母乳喂养可显著降低儿童期肥胖风险，但近期描述母乳喂养持续时间与儿童期超重或肥胖风险之间关系的文献尚无定论。
2000年11月至2001年11月期间，德国乌尔姆大学妇产科在分娩后招募了所有母亲及其新生儿。在12个月和24个月时进行了主动随访。
在纳入基线检查的1066名儿童中，855名（80%）在2年随访时有体重指数信息。在这个年龄，72名儿童（8.4%）超重，24名（2.8%）严重超重。76名儿童（8.9%）从未接受母乳喂养，533名儿童（62.3%）母乳喂养至少6个月，322名儿童（37.7%）纯母乳喂养至少6个月。与母乳喂养少于3个月的儿童相比，母乳喂养至少6个月的儿童超重的调整优势比（OR）为0.4（95%置信区间（CI）0.2 - 0.8）。在考虑纯母乳喂养时间时，与纯母乳喂养少于3个月的儿童相比，纯母乳喂养至少3个月但少于6个月的儿童超重的调整OR为0.8（95%CI 见 0.4；1.5），纯母乳喂养至少6个月的儿童超重的调整OR为0.4（95%CI 0.2；0.9）。
这些结果突出了延长母乳喂养对预防儿童超重的重要性。
