Abbas Ossama, Fares Mirna, Jamaleddine Ghassan, Arayssi Thurayya, Touma Zahi, Khalil Pierre Bou
Department of Internal Medicine, American University of Beirut Medical Center, Cairo St., Hamra, P.O. Box 11-0236, Beirut, Lebanon.
Clin Rheumatol. 2007 Feb;26(2):271-3. doi: 10.1007/s10067-005-0137-6. Epub 2006 Mar 1.
Relapsing polychondritis is characterized by recurrent inflammation and destruction of the cartilage and connective tissue. Respiratory complications are frequently severe during the course of the disease and usually signal a poor prognosis. We report a case of a 47-year-old man with known relapsing polychondritis who presented with bilateral narrowing of the airways complicated by refractory cavitary Pseudomonas aeruginosa pneumonia. Despite an aggressive antibiotic regimen, the patient's pneumonia did not improve until bronchial stenting 4 months later.
复发性多软骨炎的特征是软骨和结缔组织反复发生炎症和破坏。在疾病过程中,呼吸道并发症常常很严重,通常预示预后不良。我们报告一例47岁已知患有复发性多软骨炎的男性患者,其出现双侧气道狭窄,并伴有难治性空洞性铜绿假单胞菌肺炎。尽管采用了积极的抗生素治疗方案,但直到4个月后进行支气管支架置入术,患者的肺炎才有所改善。