Lim Wai H, McDonald Stephen P, Russ Graeme R
Renal Unit, The Queen Elizabeth Hospital, South Australia, Australia.
Nephrology (Carlton). 2006 Feb;11(1):73-7. doi: 10.1111/j.1440-1797.2006.00525.x.
The national sharing of well-matched cadaveric renal allografts has been established since 1992 in Australia. It remains uncertain whether the shipment of renal allografts interstate has a detrimental effect on graft and patient survival.
Using data collected by the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA), graft and patient survival were compared between shipped (n = 623) and locally transplanted allografts (n = 894) in Australia between January 1992 and December 2001.
Shipped renal allografts were from younger donors and had a longer ischaemic time, and were transplanted into higher risk recipients. Shipping of allografts had no effect on graft or patient survival, acute rejection at 6 months, presence of delayed graft function and serum creatinine at 6 and 12 months. In addition, human leucocyte antigen-matching and allograft ischaemic time had no effect on graft or patient survival.
Recipients of either shipped or locally transplanted well-matched renal allografts have similar graft and patient survivals.
自1992年起，澳大利亚已建立全国范围内匹配良好的尸体肾移植供体共享机制。肾移植供体在州际间运输是否会对移植肾和患者存活产生不利影响仍不明确。
利用澳大利亚和新西兰透析与移植登记处（ANZDATA）收集的数据，比较了1992年1月至2001年12月间澳大利亚运输的移植肾（n = 623）和本地移植的移植肾（n = 894）的移植肾和患者存活率。
运输的移植肾供体较年轻，缺血时间较长，且移植给了风险较高的受者。移植肾的运输对移植肾或患者存活率、6个月时的急性排斥反应、移植肾功能延迟恢复情况以及6个月和12个月时的血清肌酐水平均无影响。此外，人类白细胞抗原匹配和移植肾缺血时间对移植肾或患者存活率也无影响。
接受运输的或本地移植的匹配良好的肾移植受者，其移植肾和患者存活率相似。
