Plate Ulrich, Polifke Tobias, Sommer Dieter, Wünnenberg Jörg, Wiesmann Hans-Peter
Department of Cranio-Maxillofacial Surgery, University of Münster, Waldeyerstrasse, Münster, Germany.
Head Face Med. 2006 Mar 1;2:6. doi: 10.1186/1746-160X-2-6.
Generally animal and human cells use oxygen during their whole life. Consequently the oxygen use is a simple indicator to test the vitality of cells. When the vitality decreases by the delivery of toxic substances the decrease can be observed directly by the oxygen-use of the cells. To get fast information of the vitality of cells we have measured the O2-tension by testing a new model of a bioreactor, the Cell Vitality Checker 96 (CVC96), in practical application. With this CVC96, soon a simple test will exist for the measurement of the oxygen use. In this respect the question had to be answered whether the use in the laboratory is easy and whether oxygen as a parameter in the vitality test can also be applied in future for problems in the field of material testing.
一般来说，动物和人类细胞在其整个生命过程中都使用氧气。因此，氧气的使用是测试细胞活力的一个简单指标。当由于有毒物质的输送而导致活力下降时，可以通过细胞的氧气使用情况直接观察到这种下降。为了快速获取细胞活力信息，我们在实际应用中通过测试一种新型生物反应器——细胞活力检查仪96（CVC96）来测量氧张力。有了这个CVC96，很快就会有一个用于测量氧气使用情况的简单测试。在这方面，必须回答的问题是在实验室中使用是否容易，以及氧气作为活力测试中的一个参数在未来是否也可应用于材料测试领域的问题。
