Chen Ray Y, Accortt Neil A, Westfall Andrew O, Mugavero Michael J, Raper James L, Cloud Gretchen A, Stone Beth K, Carter Jerome, Call Stephanie, Pisu Maria, Allison Jeroan, Saag Michael S
Department of Internal Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Clin Infect Dis. 2006 Apr 1;42(7):1003-10. doi: 10.1086/500453. Epub 2006 Feb 22.
Health care expenditures for persons infected with human immunodeficiency virus (HIV) in the United State determined on the basis of actual health care use have not been reported in the era of highly active antiretroviral therapy.
Patients receiving primary care at the University of Alabama at Birmingham HIV clinic were included in the study. All encounters (except emergency room visits) that occurred within the University of Alabama at Birmingham Hospital System from 1 March 2000 to 1 March 2001 were analyzed. Medication expenditures were determined on the basis of 2001 average wholesale price. Hospitalization expenditures were determined on the basis of 2001 Medicare diagnostic related group reimbursement rates. Clinic expenditures were determined on the basis of 2001 Medicare current procedural terminology reimbursement rates.
Among the 635 patients, total annual expenditures for patients with CD4+ cell counts <50 cells/microL (36,533 dollars per patient) were 2.6-times greater than total annual expenditures for patients with CD4+ cell counts > or =350 cells/microL (13,885 dollars per patient), primarily because of increased expenditures for nonantiretroviral medication and hospitalization. Expenditures for highly active antiretroviral therapy were relatively constant at approximately 10,500 dollars per patient per year across CD4+ cell count strata. Outpatient expenditures were 1558 dollars per patient per year; however, the clinic and physician component of these expenditures represented only 359 dollars per patient per year, or 2% of annual expenses. Health care expenditures for patients with HIV infection increased substantially for those with more-advanced disease and were driven predominantly by medication costs (which accounted for 71%-84% of annual expenses).
Physician reimbursements, even with 100% billing and collections, are inadequate to support the activities of most clinics providing HIV care. These findings have important implications for the continued support of HIV treatment programs in the United States.
在高效抗逆转录病毒治疗时代,美国尚未报告根据实际医疗保健使用情况确定的感染人类免疫缺陷病毒(HIV)者的医疗保健支出。
纳入在阿拉巴马大学伯明翰分校HIV诊所接受初级保健的患者。分析了2000年3月1日至2001年3月1日在阿拉巴马大学伯明翰分校医院系统内发生的所有就诊情况(急诊室就诊除外)。药物支出根据2001年平均批发价格确定。住院支出根据2001年医疗保险诊断相关组报销率确定。诊所支出根据2001年医疗保险现行程序术语报销率确定。
在635名患者中,CD4 +细胞计数<50个细胞/微升的患者的年度总支出(每位患者36,533美元)是CD4 +细胞计数>或= 350个细胞/微升的患者的年度总支出(每位患者13,885美元)的2.6倍,主要原因是非抗逆转录病毒药物和住院支出增加。在不同CD4 +细胞计数分层中,高效抗逆转录病毒治疗的支出相对稳定,约为每位患者每年10,500美元。门诊支出为每位患者每年1558美元;然而,这些支出中的诊所和医生部分仅为每位患者每年359美元,占年度费用的2%。HIV感染患者的医疗保健支出在疾病更严重的患者中大幅增加,并且主要由药物成本驱动(药物成本占年度费用的71%-84%)。
即使进行100%的计费和收款,医生报销也不足以支持大多数提供HIV护理的诊所的活动。这些发现对美国HIV治疗项目的持续支持具有重要意义。