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[特应性疾病患儿接种疫苗后与感染性结核菌素过敏的鉴别诊断]

[Differential diagnosis of postvaccinal and infectious tuberculin allergy in children with atopic diseases].

作者信息

Borodulina E A, Borodulin B E

出版信息

Probl Tuberk Bolezn Legk. 2006(1):9-13.

Abstract

The study was undertaken to improve the quality of detection of Mycobacterium tuberculosis in children with atopic diseases. A hundred and fifty-five children with atopic diseases were examined. The standard Mantoux test with 2TE and the graded skin tuberculin test were performed. Humoral and cellular immunological parameters were investigated. Children with monotonous and age-related increasing tests presented a problem in the diagnosis of infection. The factorial analysis revealed significant immunological parameters of infectious tuberculin allergy. The increase in the detected significant immunological parameters (total IgE, IgG, IL-2, CD4+, CD8+, and CB16+ cells) was ascertained to supplement the traditional methods for tuberculin diagnosis.

摘要

开展这项研究是为了提高对患有特应性疾病儿童的结核分枝杆菌检测质量。对155名患有特应性疾病的儿童进行了检查。进行了2TE标准结核菌素试验和分级皮肤结核菌素试验。研究了体液和细胞免疫参数。试验结果单调且与年龄相关增加的儿童在感染诊断方面存在问题。因子分析揭示了感染性结核菌素过敏的重要免疫参数。确定检测到的重要免疫参数(总IgE、IgG、IL-2、CD4 +、CD8 +和CB16 +细胞)的增加可补充传统的结核菌素诊断方法。

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