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[儿童的结核菌素敏感性与结核分枝杆菌感染]

[Tuberculin susceptibility and Mycobacterium tuberculosis infection in children].

作者信息

Lebedeva L V, Gracheva S G

出版信息

Probl Tuberk Bolezn Legk. 2007(1):5-9.

Abstract

Tuberculin susceptibility was studied from the Mantoux test with 2TE in 253 children aged 14 years and during all previous years of their life. Positive tests were recorded in 72.4% of cases; doubtful tests were in 6.7%, and negative ones in 20.9%. Infection was diagnosed in 33.9 +/- 2.9%. The annual conversion of tubercular tests was 2.2 +/- 0.05%. Positive Mantoux tests with 2TE caused by the administration of BCG vaccine were observed in 45.1%, in most cases, due to persistent allergy after neonatal vaccination. The authors convince of the necessity of regularly making a tuberculin test and qualitative tuberculosis vaccines when clinically indicated.

摘要

对253名14岁儿童及其以往各年龄段进行了用2TE结核菌素进行的结核菌素敏感性曼托试验研究。72.4%的病例检测呈阳性;可疑检测占6.7%,阴性检测占20.9%。诊断感染率为33.9±2.9%。结核菌素试验的年转化率为2.2±0.05%。45.1%的病例观察到因接种卡介苗导致的2TE曼托试验阳性,在大多数情况下,是由于新生儿接种后持续过敏。作者坚信,在临床有指征时定期进行结核菌素试验和使用定性结核疫苗的必要性。

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