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Successful use of genotypic resistance testing in HIV-1-infected individuals with detectable viraemia between 50 and 1000 copies/ml.

作者信息

Waters Laura, Mandalia S, Asboe David

机构信息

Department of Genitourinary and HIV Medicine, St Stephens Centre, Chelsea and Westminster Hospital, London, UK.

出版信息

AIDS. 2006 Mar 21;20(5):778-9. doi: 10.1097/01.aids.0000216381.37679.69.

Abstract

Traditionally an HIV viral load of over 1000 copies/ml was presumed necessary for genotypic resistance testing. We performed a retrospective analysis to assess rates of viral amplification on viral loads between 50 and 1000 copies/ml. Amplification was significantly more likely for 200-1000 copies/ml than 50-200 copies/ml; most samples amplified successfully, supporting the use of genotyping for low-level viraemia.

摘要

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