Rao S K, Rao P S
Department of Orthopaedics, KMC Hospital, Manipal 576 104 (Udupi Dist), Karnataka State, India.
Med J Malaysia. 2005 Dec;60(5):560-2.
Post Arthroscopic intra-articular analgesia is a better method to avoid post-operative pain after arthroscopic surgery, thus avoiding the adverse effects of systemic analgesics. In this prospective randomized double blind study conducted on 90 patients, 30 patients in group A received 20 ml of intra-articular saline, 30 patients in Group B received 10 ml of intra-articular saline and 10 ml of 0.25% bupivacaine and 30 patients in Group C received 10 ml of 0.25% bupivacaine, 1 ml (30 mg) of ketorolac and 9 ml of saline intra-articularly. Ambulatory status, duration of analgesia and requirement for supplemented analgesia were compared in these three groups. Patients receiving this intra-articular analgesic combination of bupivacaine and ketorolac required significantly less supplemental postoperative analgesics. This combination significantly prolonged the duration of analgesia. Patients receiving this combination of drugs for intra-articular analgesia ambulated earlier.
关节镜术后关节内镇痛是避免关节镜手术后疼痛的更好方法,从而避免全身镇痛药的不良反应。在这项对90例患者进行的前瞻性随机双盲研究中,A组30例患者接受20ml关节内生理盐水,B组30例患者接受10ml关节内生理盐水和10ml 0.25%布比卡因,C组30例患者接受10ml 0.25%布比卡因、1ml(30mg)酮咯酸和9ml生理盐水关节内注射。比较这三组患者的活动状态、镇痛持续时间和补充镇痛的需求。接受布比卡因和酮咯酸这种关节内镇痛联合用药的患者术后所需补充镇痛药明显较少。这种联合用药显著延长了镇痛持续时间。接受这种关节内镇痛联合用药的患者更早开始活动。