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酷似晚期卵巢癌的腹膜结核:仅凭临床印象就足以对晚期卵巢癌施行新辅助化疗吗?

Peritoneal tuberculosis simulating advanced ovarian carcinoma: is clinical impression sufficient to administer neoadjuvant chemotherapy for advanced ovarian cancer?

作者信息

Gurbuz A, Karateke A, Kabaca C, Kir G, Cetingoz E

机构信息

Department of Obstetrics and Gynecology, Zeynep Kamil Women and Children Diseases Education and Research Hospital, Uskudar, Istanbul, Turkey.

出版信息

Int J Gynecol Cancer. 2006 Jan-Feb;16 Suppl 1:307-12. doi: 10.1111/j.1525-1438.2006.00209.x.

DOI:10.1111/j.1525-1438.2006.00209.x
PMID:16515610
Abstract

Peritoneal tuberculosis mimics advanced ovarian cancer because of the similarities in clinical signs and symptoms such as ascites, pelvic and abdominal pain and mass, and elevation of serum CA125 level. We have presented four cases of peritoneal tuberculosis that underwent exploratory laparotomy for suspected advanced ovarian cancer during a 3-year period. Definitive diagnosis of tuberculosis was performed at laparotomy in all the cases. The frozen-section analysis seems to be the gold standard in the differential diagnosis. In view of these data, clinical diagnosis of advanced ovarian cancer is not sufficient for administering neoadjuvant chemotherapy. Cytologic or pathologic findings must be consistent with ovarian cancer for candidates who are being considered for neoadjuvant chemotherapy.

摘要

由于腹膜结核在临床体征和症状上与晚期卵巢癌相似,如腹水、盆腔和腹部疼痛及肿块,以及血清CA125水平升高,因此腹膜结核易被误诊为晚期卵巢癌。我们报告了4例腹膜结核患者,在3年期间因疑似晚期卵巢癌接受了剖腹探查术。所有病例均在剖腹手术时确诊为结核。冷冻切片分析似乎是鉴别诊断的金标准。鉴于这些数据,晚期卵巢癌的临床诊断不足以进行新辅助化疗。对于考虑接受新辅助化疗的患者,细胞学或病理结果必须与卵巢癌一致。

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Peritoneal tuberculosis simulating advanced ovarian carcinoma: is clinical impression sufficient to administer neoadjuvant chemotherapy for advanced ovarian cancer?酷似晚期卵巢癌的腹膜结核:仅凭临床印象就足以对晚期卵巢癌施行新辅助化疗吗?
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Familial tuberculosis mimicking advanced ovarian cancer.
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Infect Dis Obstet Gynecol. 2009;2009:736018. doi: 10.1155/2009/736018. Epub 2009 Dec 21.