Khalbuss W E, Dipasquale B
Department of Pathology, University of Florida Health Science Center (UFHSC), Jacksonville, Florida 32209, USA.
Int J Gynecol Cancer. 2006 Jan-Feb;16 Suppl 1:326-30. doi: 10.1111/j.1525-1438.2006.00368.x.
Massive ovarian edema is a rare entity that can be confused with an ovarian neoplasm. A few ovarian lesions have been reported that are associated with massive ovarian edema. This article describes the first case of an ovarian serous cystadenoma associated with a massive ovarian edema. The patient was a 17-year-old female who was referred to the emergency room because of lower abdominal pain. Subsequent ultrasound and computed tomography scanning studies revealed an abdominopelvic cystic mass suggestive of an ovarian neoplasm. She underwent an exploratory laparoscopy, and a left salpingo-oophorectomy was performed. The specimen weighed 1610 g and consisted of a cystic mass measuring 17 x 15 x 8 cm attached to a solid mass measuring 13 x 11 x 4 cm. Microscopy revealed a cystic and a solid lesion. The cystic structure was composed of a flat or cuboidal single-layer lining showing ciliated epithelium and focal areas of papillary structures compatible with a diagnosis of ovarian serous cystadenoma. The solid mass had an intact capsule and diffuse interstitial edema, preserving the overall structure of the ovary and sparing the outer cortex. These findings are compatible with the diagnosis of ovarian massive edema. This report of an association of serous cystadenoma with massive ovarian edema broadens the histologic spectrum in which a massive ovarian edema may be encountered.
巨大卵巢水肿是一种罕见的病症，可能会与卵巢肿瘤相混淆。已有少数与巨大卵巢水肿相关的卵巢病变的报道。本文描述了首例与巨大卵巢水肿相关的卵巢浆液性囊腺瘤病例。患者为一名17岁女性，因下腹部疼痛被转诊至急诊室。随后的超声和计算机断层扫描研究显示腹盆腔有一个囊性肿块，提示为卵巢肿瘤。她接受了 exploratory laparoscopy（此处英文有误，推测可能是“exploratory laparotomy”，即剖腹探查术），并进行了左侧输卵管卵巢切除术。标本重1610克，由一个17×15×8厘米的囊性肿块和一个附着在其上的13×11×4厘米的实性肿块组成。显微镜检查显示一个囊性和一个实性病变。囊性结构由单层扁平或立方形内衬组成，显示有纤毛上皮以及与卵巢浆液性囊腺瘤诊断相符的乳头结构的局灶性区域。实性肿块有完整的包膜和弥漫性间质水肿，保留了卵巢的整体结构并未累及外层皮质。这些发现与卵巢巨大水肿的诊断相符。这例浆液性囊腺瘤与巨大卵巢水肿相关的报道拓宽了可能遇到巨大卵巢水肿的组织学范围。
