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[3H]1,3-Di(2-tolyl)guanidine labels two high affinity binding sites in guinea pig brain: evidence for allosteric regulation by calcium channel blockers and sigma ligands.

作者信息

Rothman R B, Mahboubi A, Reid A A, Kim C H, deCosta B R, Jacobson A E, Rice K C

机构信息

Unit on Receptor Studies, LCS, NIMH, Bethesda, MD 20892.

出版信息

NIDA Res Monogr. 1990;105:335-6.

PMID:1652074
Abstract
摘要

相似文献

1
[3H]1,3-Di(2-tolyl)guanidine labels two high affinity binding sites in guinea pig brain: evidence for allosteric regulation by calcium channel blockers and sigma ligands.[3H]1,3-二(2-甲苯基)胍标记豚鼠脑中的两个高亲和力结合位点:钙通道阻滞剂和西格玛配体变构调节的证据。
NIDA Res Monogr. 1990;105:335-6.
2
Labeling by [3H]1,3-di(2-tolyl)guanidine of two high affinity binding sites in guinea pig brain: evidence for allosteric regulation by calcium channel antagonists and pseudoallosteric modulation by sigma ligands.用[3H]1,3 - 二(2 - 甲苯基)胍标记豚鼠脑中的两个高亲和力结合位点:钙通道拮抗剂的变构调节及西格玛配体的拟变构调节的证据
Mol Pharmacol. 1991 Feb;39(2):222-32.
3
Multiple [3H]DTG binding sites in guinea pig cerebellum: evidence for the presence of non-specific binding.豚鼠小脑中多个[3H]DTG结合位点:非特异性结合存在的证据。
Eur J Pharmacol. 1994 Feb 3;252(2):139-46. doi: 10.1016/0014-2999(94)90589-4.
4
1,3-Di(2-[5-3H]tolyl)guanidine: a selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugs.
Proc Natl Acad Sci U S A. 1986 Nov;83(22):8784-8. doi: 10.1073/pnas.83.22.8784.
5
[3H]BIMU-1, a 5-hydroxytryptamine3 receptor ligand in NG-108 cells, selectively labels sigma-2 binding sites in guinea pig hippocampus.[3H]BIMU-1,一种在NG-108细胞中的5-羟色胺3受体配体,可选择性标记豚鼠海马体中的σ-2结合位点。
J Pharmacol Exp Ther. 1993 Nov;267(2):961-70.
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Identification of the binding subunit of the sigma-type opiate receptor by photoaffinity labeling with 1-(4-azido-2-methyl[6-3H]phenyl)-3-(2-methyl[4,6-3H]phenyl)guanidine.通过用1-(4-叠氮基-2-甲基[6-³H]苯基)-3-(2-甲基[4,6-³H]苯基)胍进行光亲和标记来鉴定σ型阿片受体的结合亚基。
Proc Natl Acad Sci U S A. 1988 Apr;85(8):2844-8. doi: 10.1073/pnas.85.8.2844.
7
Binding of sigma-ligands to C57BL/6 mouse brain membranes: effects of monoamine oxidase inhibitors and subcellular distribution studies suggest the existence of sigma-receptor subtypes.σ配体与C57BL/6小鼠脑膜的结合:单胺氧化酶抑制剂的作用及亚细胞分布研究提示σ受体亚型的存在。
J Pharmacol Exp Ther. 1991 Apr;257(1):141-8.
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1,3-Di(2-tolyl)guanidine blocks nicotinic response in guinea pig myenteric neurons.
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Autoradiographic visualization of haloperidol-sensitive sigma receptors in guinea-pig brain.豚鼠脑中氟哌啶醇敏感型σ受体的放射自显影可视化
Neuroscience. 1988 Apr;25(1):259-69. doi: 10.1016/0306-4522(88)90024-3.
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[3H]RS-23597-190, a potent 5-hydroxytryptamine4 antagonist labels sigma-1 but not sigma-2 binding sites in guinea pig brain.[3H]RS - 23597 - 190,一种强效的5 - 羟色胺4拮抗剂,可标记豚鼠脑中的σ-1而非σ-2结合位点。
J Pharmacol Exp Ther. 1994 Oct;271(1):484-93.

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