Goh T C, Ong Y Y
Department of Medicine III, Singapore General Hospital.
Singapore Med J. 1991 Jun;32(3):183-4.
Cough is a recognised side effect of angiotensin converting enzyme (ACE) inhibitors although its exact mechanism is still unknown. Reports on the side effect of ACE inhibitors on asthma have been conflicting. These drugs either had no effect on bronchial reactivity or resulted in an increase in pre-existing hyperreactivity. We report a case of a non-asthmatic patient who had lisinopril-induced cough and bronchial hyperreactivity.
咳嗽是血管紧张素转换酶(ACE)抑制剂公认的副作用,但其确切机制仍不清楚。关于ACE抑制剂对哮喘副作用的报道相互矛盾。这些药物要么对支气管反应性没有影响,要么导致已有的高反应性增加。我们报告一例非哮喘患者,该患者出现赖诺普利诱发的咳嗽和支气管高反应性。