Davis Faith G, Erdal Serap, Williams Lori, Bigner Darell
Department of Epidemiology, School of Public Health, University of Illinois at Chicago, Illinois 60612, USA.
Int J Occup Environ Health. 2006 Jan-Mar;12(1):16-23. doi: 10.1179/oeh.2006.12.1.16.
The initiation of brain tumors has been demonstrated in animals exposed to industrial chemicals, results which have not been demonstrated in humans. This report describes the National Occupation Exposure Survey conducted by the National Institute of Occupational Safety and Health during the years 1981-1983, which included information about 16 known and suspected animal neurocarcinogens. Acrylonitrile, ethylene oxide, and 1-H-benzotriazole had national exposure estimates of more than 50,000 workers. The health services industry had the largest number of workers potentially exposed to a single agent and the most diverse exposures in the workplace. These data provide some evidence for the pattern and presence of animal neurocarcinogens in the occupational environment and provide a basis on which to begin to develop occupational exposure tools and to prioritize further research.
在接触工业化学品的动物身上已证实会引发脑肿瘤，但在人类身上尚未得到证实。本报告描述了美国国家职业安全与健康研究所于1981年至1983年期间进行的全国职业接触调查，其中包括有关16种已知和疑似动物神经致癌物的信息。丙烯腈、环氧乙烷和1 - H - 苯并三唑的全国接触估计数超过50000名工人。卫生服务行业潜在接触单一化学品的工人数量最多，且工作场所的接触情况最为多样。这些数据为职业环境中动物神经致癌物的模式和存在提供了一些证据，并为开始开发职业接触工具和确定进一步研究的优先级提供了依据。
