Papapetropoulos Spiridon, Lieberman Abraham, Gonzalez Jocely, Singer Carlos, Laufer Daniel Z, Mash Deborah C
Department of Neurology, University of Miami, Miller School of Medicine, Miami Fl, 33136, USA.
J Neuropsychiatry Clin Neurosci. 2006 Winter;18(1):113-6. doi: 10.1176/jnp.18.1.113.
Parkinson's disease with dementia (PD-D) and dementia with Lewy bodies (DLB) may result from the same neurodegenerative process with different temporal and spatial courses. The authors report an association between DLB and family history of dementia in a comparison study between patients with a clinicopathological diagnosis of PD-D and DLB. Findings suggest that positive family history for dementia is associated with DLB with a yet unknown mechanism.
帕金森病痴呆（PD-D）和路易体痴呆（DLB）可能源于相同的神经退行性过程，但具有不同的时间和空间进程。在一项对临床病理诊断为PD-D和DLB的患者进行的比较研究中，作者报告了DLB与痴呆家族史之间的关联。研究结果表明，痴呆的阳性家族史与DLB相关，但其机制尚不清楚。
