Hwang Y H, Person B, Choi J S, Nam Y S, Singh J J, Weiss E G, Nogueras J J, Wexner S D
Department of Colorectal Surgery, Cleveland Clinic Florida, 2950 Cleveland Clinic Blvd., Weston, FL 33331, USA.
Tech Coloproctol. 2006 Mar;10(1):11-5; discussion 15-6. doi: 10.1007/s10151-006-0244-7. Epub 2006 Mar 15.
Surgery for isolated internal rectal intussusception is controversial due to high morbidity. Therefore, there is interest in other forms of treatment that are safe and effective. The aim of this study was to determine outcome and identify predictors for success of biofeedback therapy in patients with rectal intussusception.
We retrospectively evaluated the results of electromyography (EMG)-based biofeedback in 34 patients with rectal intussusception without any other major pelvic floor or colonic physiologic disorder.
A total of 34 patients (7 men) had undergone at least 2 biofeedback sessions. The patients had a mean age of 68.5 years (SD=11.4 years). In the 27 patients with constipation, the frequency of weekly spontaneous bowel movements (mean+/-SD) was 2.0+/-6.8 before and 4.1+/-4.6 after biofeedback (p<0.05). The frequency of weekly assisted bowel movements decreased from 3.8+/-3.5 before to 1.5+/-2.2 after therapy (p<0.005). The number of patients who experienced incomplete evacuation decreased from 17 (63%) to 9 (33%) (p<0.05). Thirty-three percent of patients had complete resolution of the symptoms, 19% had partial improvement, and 48% had no improvement. Patients with constipation lasting less than nine years had a 78% success rate vs. 13% in patients who were constipated more than 9 years (p<0.01). In seven patients with incontinence, the frequency of daily incontinence episodes decreased from 1.0+/-0.7 before to 0.07+/-0.06 after biofeedback (p<0.05). The fecal incontinence score decreased from 13.1+/-4.2 before to 4.6+/-3.6 after treatment (p<0.005). Two patients (29%) were completely continent following biofeedback, 2 had partial improvement, and 3 (43%) had no significant improvement. There was no mortality in either group.
Biofeedback is a safe and effective treatment option for constipation and fecal incontinence due to rectal intussusception in patients who are willing to complete the course of treatment. Long-standing constipation is less effectively cured by biofeedback.
由于高发病率,孤立性直肠内套叠的手术存在争议。因此,人们对其他安全有效的治疗形式感兴趣。本研究的目的是确定直肠套叠患者生物反馈治疗的结果并识别成功的预测因素。
我们回顾性评估了34例无任何其他主要盆底或结肠生理紊乱的直肠套叠患者基于肌电图(EMG)的生物反馈结果。
共有34例患者(7例男性)接受了至少2次生物反馈治疗。患者的平均年龄为68.5岁(标准差=11.4岁)。在27例便秘患者中,每周自发排便频率(均值±标准差)在生物反馈前为2.0±6.8次,之后为4.1±4.6次(p<0.05)。每周辅助排便频率从治疗前的3.8±3.5次降至治疗后的1.5±2.2次(p<0.005)。经历排便不尽的患者数量从17例(63%)降至9例(33%)(p<0.05)。33%的患者症状完全缓解,19%部分改善,48%无改善。便秘持续时间少于9年的患者成功率为78%,而便秘超过9年的患者成功率为13%(p<0.01)。在7例大便失禁患者中,每日失禁发作频率从生物反馈前的1.0±0.7次降至0.07±0.06次(p<0.05)。大便失禁评分从治疗前的13.1±4.2降至治疗后的4.6±3.6(p<0.005)。2例患者(29%)在生物反馈治疗后完全控便,2例部分改善,3例(43%)无明显改善。两组均无死亡病例。
对于愿意完成治疗疗程的直肠套叠所致便秘和大便失禁患者,生物反馈是一种安全有效的治疗选择。生物反馈对长期便秘的治愈率较低。