Fraquelli Mirella, Sciola Valentina, Villa Chiara, Conte Dario
Postgraduate School of Gastroenterology, Padiglione Granelli 3 degû piano, Fondazione IRCCS Ospedale Maggiore Policlinico, Via F. Sforza 35, 20122 Milano, Italy.
World J Gastroenterol. 2006 Feb 21;12(7):1001-4. doi: 10.3748/wjg.v12.i7.1001.
The aim of the present review was to summarize the current evidence on the role of ultrasonography (US) and doppler-US in the diagnosis of celiac disease. Several ultrasonographic signs have been reported in the association with celiac disease in studies using real-time US. Firstly, case control studies identified some of these US signs and then in a prospective series some of these parameters, due to their high specificity, have been shown to be of value in confirming CD diagnosis, whereas others, due to their high sensitivity, have been demonstrated to be useful in excluding the presence of the disease. The pattern of splanchnic circulation in CD have extensively been investigated by several studies all of which reported similar results and identified a hyperdynamic mesenteric circulation that reverts to normal values after successful a gluten-free regimen. The last part of this review will deal with the possible role of US in identifying the most severe and common intestinal complication of CD, i.e. the enteropathy-associated T cell non-Hodgkin lymphoma.
本综述的目的是总结目前关于超声检查(US)和多普勒超声在乳糜泻诊断中作用的证据。在使用实时超声的研究中,已经报道了几种与乳糜泻相关的超声征象。首先,病例对照研究确定了其中一些超声征象,然后在前瞻性系列研究中,由于其高特异性,其中一些参数已被证明对确诊乳糜泻有价值,而其他一些参数,由于其高敏感性,已被证明有助于排除该病的存在。多项研究对乳糜泻患者内脏循环模式进行了广泛研究,所有研究均报告了相似结果,并确定了肠系膜循环动力亢进,在成功采用无麸质饮食方案后可恢复至正常水平。本综述的最后一部分将探讨超声在识别乳糜泻最严重和最常见的肠道并发症即肠病相关T细胞非霍奇金淋巴瘤方面的可能作用。