Jovićević Jasna, Kljajić Vladimir
Srp Arh Celok Lek. 2005 Dec;133 Suppl 2:105-7. doi: 10.2298/sarh05s2105j.
Nasal polyposis is a multifactor disease characterised by chronic eosinophilic inflammation of the nasal and sinal mucosae. Its aetiology is unknown, but it's often associated with other diseases: allergic rhinitis, asthma, and aspirin sensitivity in adult patients. In children, mucoviscidosis is possible. The aim of this paper is to determine the relationship between nasal polyposis and allergic rhinitis, and their link with idiopathic rhinitis. The study involved 100 patients of both sexes. Patients were divided into three groups: group I--with allergic rhinitis (65 patients), group II--with idiopathic rhinitis (25 patients), and group III--without any diseases of the upper airways (10 patients). All patients underwent ENT examinations, blood laboratory and microbiology tests, RTG tests, as well as skin prick tests on inhalant allergens. In the group with allergic rhinitis, 21 patients had nasal polyposis. In the group with idiopathic rhinitis, 7 patients had nasal polyposis. In the control group, all the patients exhibited normal endonasal findings. Statistically significant difference was present only between the group of patients with allergic rhinitis and the control group (p=0.034). Nasal polyposis is related to allergic rhinitis, although the reason why polyposis develops in some patients and not in others remains unknown.
鼻息肉病是一种多因素疾病，其特征为鼻腔和鼻窦黏膜的慢性嗜酸性粒细胞炎症。其病因不明，但常与其他疾病相关：成年患者中的过敏性鼻炎、哮喘和阿司匹林敏感性。在儿童中，可能患有黏液黏稠病。本文的目的是确定鼻息肉病与过敏性鼻炎之间的关系，以及它们与特发性鼻炎的联系。该研究纳入了100名男女患者。患者被分为三组：第一组——患有过敏性鼻炎（65例患者），第二组——患有特发性鼻炎（25例患者），第三组——无上呼吸道疾病（10例患者）。所有患者均接受了耳鼻喉科检查、血液实验室和微生物学检查、RTG检查以及吸入性过敏原皮肤点刺试验。在患有过敏性鼻炎的组中，21例患者患有鼻息肉病。在患有特发性鼻炎的组中，7例患者患有鼻息肉病。在对照组中，所有患者的鼻内检查结果均正常。仅在患有过敏性鼻炎的患者组与对照组之间存在统计学显著差异（p = 0.034）。鼻息肉病与过敏性鼻炎相关，尽管部分患者发生息肉病而其他患者未发生的原因尚不清楚。
