Raymond J D, Ojala T A, White J, Simmons M J
Department of Genetics and Cell Biology, University of Minnesota, St Paul 55108-1095.
Genet Res. 1991 Jun;57(3):227-34. doi: 10.1017/s0016672300029372.
The ability to repress P-element-induced gonadal dysgenesis was studied in 14 wild-type strains of D. melanogaster derived from populations in the central and eastern United States. Females from each of these strains had a high ability to repress gonadal dysgenesis in their daughters. Reciprocal hybrids produced by crossing each of the wild-type strains with an M strain demonstrated that repression ability was determined by a complex mixture of chromosomal and cytoplasmic factors. Cytoplasmic transmission of repression ability was observed in all 14 strains and chromosomal transmission was observed in 12 of them. Genomic Southern blots indicated that four of the strains possessed a particular type of P element, called KP, which has been proposed to account for the chromosomal transmission of repression ability. However, in this study several of the strains that lacked KP elements exhibited as much chromosomal transmission of repression ability as the strains that had KP elements, suggesting that other kinds of P elements may be involved.
对来自美国中部和东部种群的14个黑腹果蝇野生型品系抑制P因子诱导的性腺发育不全的能力进行了研究。这些品系中的每一个品系的雌性都具有很高的抑制其女儿性腺发育不全的能力。将每个野生型品系与一个M品系杂交产生的正反交杂种表明，抑制能力由染色体和细胞质因子的复杂混合物决定。在所有14个品系中都观察到了抑制能力的细胞质传递，在其中12个品系中观察到了染色体传递。基因组Southern杂交表明，其中四个品系拥有一种特殊类型的P因子，称为KP，有人提出它可解释抑制能力的染色体传递。然而，在本研究中，几个缺乏KP因子的品系表现出与具有KP因子的品系一样多的抑制能力的染色体传递，这表明可能涉及其他种类的P因子。
