Nayar Suprabha, Pramanick Ashit Kumar, Sharma Binay Kumar, Mishra Rahul Kumar, Bansal Satyendra Kumar, Prajapati Amardeep, Sahu Kaushal Kishor, Das Swapan Kr, Pathak Lokesh, Sinha Arvind
National Metallurgical laboratory, Materials Characterization Division, Jamshedpur 831007, India.
Colloids Surf B Biointerfaces. 2006 Mar 15;48(2):183-7. doi: 10.1016/j.colsurfb.2005.09.006.
A biomimetic process for coating of nanosized hydroxyapatite on stainless steel, which capitalises the dual nature of the protein bovine serum albumin in both metal binding and a strong affinity for calcium ions, has been developed. The novelty of the process lies in pre-conditioning the metallic surface using the above protein prior to its mineralization with hydroxyapatite at ambient conditions. The microporous morphology of these coatings may provide favourable solubility and resorbability as desired by many orthopaedic and orthodontic applications.
一种在不锈钢上涂覆纳米级羟基磷灰石的仿生工艺已经开发出来，该工艺利用了蛋白质牛血清白蛋白在金属结合和对钙离子具有强亲和力方面的双重特性。该工艺的新颖之处在于，在室温条件下用羟基磷灰石使其矿化之前，先用上述蛋白质对金属表面进行预处理。这些涂层的微孔形态可能会提供许多骨科和正畸应用所需的良好溶解性和可吸收性。
