Meisner H, Czech M P
Program in Molecular Medicine, University of Massachusetts Medical School, Worcester 10605.
Curr Opin Cell Biol. 1991 Jun;3(3):474-83. doi: 10.1016/0955-0674(91)90076-b.
Casein kinase II is involved in the phosphorylation of several proto-oncogenes, anti-oncogenes, and oncogenes that are nuclear transcriptional regulatory factors. The potential functions of the phosphorylations in each of these proteins are evaluated. New findings indicate that casein kinase II is a critical component of the mechanisms regulating the cell cycle.
酪蛋白激酶II参与多种原癌基因、抗癌基因和作为核转录调节因子的癌基因的磷酸化过程。对这些蛋白质中每种蛋白质磷酸化的潜在功能进行了评估。新的研究结果表明，酪蛋白激酶II是调节细胞周期机制的关键组成部分。
