Schulte Rolf F, Lange Thomas, Beck Johannes, Meier Dieter, Boesiger Peter
Institute for Biomedical Engineering, University and ETH Zurich, CH-8092 Zurich, Switzerland.
NMR Biomed. 2006 Apr;19(2):264-70. doi: 10.1002/nbm.1027.
Localised two-dimensional J-resolved spectroscopy (JPRESS) is optimised for the in vivo detection of J-coupled metabolites using magnetic resonance spectroscopy at 3 T. The acquisition of echo signals starts as early as possible (i.e. maximum-echo sampling). This sampling scheme increases sensitivity and decreases overlap of peak tails, hence alleviating baseline problems. Reconstruction issues are discussed and the sensitivity is compared analytically with that of 1D PRESS. The qualitative behaviour of eddy currents in JPRESS is outlined and a 2D eddy current correction procedure based on the 1D phase deconvolution method is proposed.
局部二维J分辨谱(JPRESS)针对在3T磁场下使用磁共振波谱进行体内J耦合代谢物检测进行了优化。回波信号的采集尽早开始(即最大回波采样)。这种采样方案提高了灵敏度,减少了峰尾重叠,从而缓解了基线问题。讨论了重建问题,并将灵敏度与一维PRESS的灵敏度进行了分析比较。概述了JPRESS中涡流的定性行为,并提出了一种基于一维相位反卷积方法的二维涡流校正程序。