Ledouarin B, Régnier B, O'Byrne P, Loisance D, Laurent F, Yvart J, Cachéra J P, Galey J J
Ann Anesthesiol Fr. 1977;18(1):35-42.
The variations in protein, bodyweight and circulating blood volume during operation are studied in 18 patients operated under ECC. The frequency of hypovolemia with hypoproteinemia and over hydration of the interstitial medium is confirmed. The prolongation of ECC beyond 120 minutes is accompanied by a considerable reduction in the plasma sector. The frequency of hypovolemia must render the use of diuretics prudent. The existence of hypoproteinemia and interstitial overload suggests the value of albumin perfusions.
对18例在体外循环（ECC）下手术的患者术中蛋白质、体重和循环血容量的变化进行了研究。证实了低血容量伴低蛋白血症以及间质液过度水化的发生频率。体外循环时间超过120分钟会伴随血浆量显著减少。低血容量的发生频率使得使用利尿剂需谨慎。低蛋白血症和间质液超负荷的存在表明了输注白蛋白的价值。
