Scheid R, Voltz R, Briest S, Kluge R, von Cramon D Y
Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
J Neurol Neurosurg Psychiatry. 2006 Apr;77(4):529-30. doi: 10.1136/jnnp.2005.082206.
Neuroimaging is usually unremarkable in paraneoplastic cerebellar degeneration (PCD), at least in the early stages of the disease. A patient with proven PCD is reported in whom it could be shown that cerebellar atrophy evolved very rapidly and was present in early imaging studies. Even with the use of the whole spectrum of modern diagnostic tools, the underlying malignancy can be difficult to diagnose. In addition to mammography, MRI is recommended in these cases and repeat FDG-PET may be necessary.
神经影像学检查在副肿瘤性小脑变性(PCD)中通常无明显异常,至少在疾病早期如此。本文报告了一例确诊为PCD的患者,其小脑萎缩在早期影像学检查中即已出现,且进展非常迅速。即便使用了所有现代诊断工具,仍可能难以诊断出潜在的恶性肿瘤。除乳腺钼靶检查外,这些病例建议进行MRI检查,可能还需要重复进行FDG-PET检查。