Choi K-D, Kim J S, Park S-H, Kim Y K, Kim S E, Smitt P S
Department of Neurology, College of Medicine, Seoul National University, Republic of Korea.
J Neurol Neurosurg Psychiatry. 2006 Apr;77(4):525-8. doi: 10.1136/jnnp.2005.075325.
A 51 year old man with paraneoplastic cerebellar degeneration from gastric adenocarcinoma showed cerebellar hypermetabolism and increased perfusion on brain FDG-PET scan and SPECT during the acute stage of his illness. The patient underwent subtotal gastrectomy. The intensity of the hypermetabolism had decreased markedly on follow-up FDG-PET 3 months later following two cycles of chemotherapy. We suggest that the cerebellar hypermetabolism may have been due to an acute inflammatory process associated with an immunological reaction.
一名51岁患有胃癌所致副肿瘤性小脑变性的男性患者,在疾病急性期的脑部氟代脱氧葡萄糖正电子发射断层扫描(FDG-PET)及单光子发射计算机断层扫描(SPECT)检查中显示小脑代谢亢进及灌注增加。该患者接受了胃大部切除术。在两个周期化疗后的3个月随访FDG-PET检查中,代谢亢进的强度显著降低。我们认为小脑代谢亢进可能是由于与免疫反应相关的急性炎症过程所致。