Soop Mattias, Nygren Jonas, Ljungqvist Olle
Karolinska Institute, CLINTEC, Karolinska University Hospital Huddinge and Centre for Gastrointestinal Disease, Ersta Hospital, Stockholm, Sweden.
Curr Opin Crit Care. 2006 Apr;12(2):166-70. doi: 10.1097/01.ccx.0000216586.62125.6d.
This review highlights recent developments in individual perioperative interventions in colorectal surgery, and progress in so-called fast-track or enhanced-recovery programmes.
A new survey from five northern European countries has revealed that best clinical practice in perioperative care, based on previously published high-grade evidence, is only partially in use in daily clinical practice. Recently, a number of trials contrasting clinical results in enhanced-recovery protocols versus traditional care clearly show that such protocols indeed enhance recovery, although effects on morbidity are less obvious. Further evidence supporting preoperative oral carbohydrate treatment, avoidance of oral bowel preparation and wound drainage in elective colonic surgery and avoidance of intraoperative fluid excess has emerged. The oral opioid antagonist alvimopan has recently been shown to limit postoperative gastrointestinal paralysis. The role of laparoscopic surgery in the era of enhanced-recovery programmes is unclear.
There is strong evidence on how to enhance recovery after colorectal surgery, but many interventions are not utilized in daily practice. Further evidence has emerged supporting several perioperative treatments, and successful experiences of enhanced-recovery programmes have now been reported from several centres.
本综述重点介绍了结直肠手术中个体围手术期干预措施的最新进展,以及所谓的快速康复或强化康复计划的进展。
一项来自北欧五个国家的新调查显示,基于先前发表的高级别证据的围手术期护理最佳临床实践,在日常临床实践中仅部分得到应用。最近,一些对比强化康复方案与传统护理临床结果的试验清楚地表明,此类方案确实能促进康复,尽管对发病率的影响不太明显。进一步的证据支持术前口服碳水化合物治疗、避免择期结肠手术中的口服肠道准备和伤口引流以及避免术中液体过量。口服阿片类拮抗剂阿维莫潘最近已被证明可限制术后胃肠麻痹。在强化康复计划时代,腹腔镜手术的作用尚不清楚。
有充分证据表明如何促进结直肠手术后的康复,但许多干预措施在日常实践中并未得到应用。进一步的证据支持了几种围手术期治疗方法,现在已有多个中心报道了强化康复计划的成功经验。