Paradisi F, Graziano L, de Ritis F
Pathol Biol (Paris). 1975 Feb;23(2):101-5.
The authors studied the modifications of the activities of some enzymes in cell cultures submitted to the action of biliverdin. This biliary pigment rapidly induces a remarkable increase in alkaline phosphatase and ATP-ase activities and subsequently, an activation of acid phosphatase and beta-glucuronidase. On the contrary, 5'-nucleotidase and glucose-6-phosphatase activities remain unchanged. These results are discussed and compared with those obtained in our and other laboratories by using unconjugated bilirubin on different biological substrates.
作者研究了暴露于胆绿素作用下的细胞培养物中某些酶活性的变化。这种胆汁色素迅速导致碱性磷酸酶和ATP酶活性显著增加，随后酸性磷酸酶和β-葡萄糖醛酸酶被激活。相反，5'-核苷酸酶和葡萄糖-6-磷酸酶活性保持不变。对这些结果进行了讨论，并与我们实验室和其他实验室使用未结合胆红素在不同生物底物上获得的结果进行了比较。
