中国肥胖人群中胃内球囊的应用：初步经验

Intragastric balloon in ethnic obese Chinese: initial experience.

作者信息

Mui Wilfred Lik-Man, So Wing-Yee, Yau Phyllis Yin-Ping, Lam Chuen Hing, Yung Man Yee, Cheng Angela Yuen-Shan, Chow Francis Chun Chung, Ng Enders Kwok-Wai

机构信息

Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.

出版信息

Obes Surg. 2006 Mar;16(3):308-13. doi: 10.1381/096089206776116516.

DOI:10.1381/096089206776116516

PMID:16545162

Abstract

BACKGROUND

We evaluated the effectiveness and safety of intragastric balloon (IGB) for the treatment of obesity in ethnic Chinese in Hong Kong.

METHODS

15 Chinese patients (10 females; median age 40 years (range 21-58)) completed IGB treatment over a 10-month period since November 2004. Median baseline body weight (BW) and BMI were 100.1 (range 78.5-170.3) kg and 39.4 (range 29.6-56.9) kg/m2 respectively. Coexistent obesity-related morbidities were present in 80% of patients. The Bioenterics Intragastric Balloon (BIB) was employed, and all placement and removal were performed endoscopically under intravenous conscious sedation. A restricted balanced diet (approximately 1200 kcal/day) and 150 minutes/week of moderate-intensity exercise were prescribed after balloon placement in a multidisciplinary approach. Outcome measures were collected and assessed in a prospective manner.

RESULTS

Median procedure time was 25 (range 19-45) minutes and median hospital stay was 2 (range 1-6) days. Median BW and BMI loss were 15.3 (range 5.3-30.9) kg and 5.6 (range 1.9-12.5) kg/m2 after IGB. The median waist circumference (WC) loss was 9 (range 4-23) cm, and 66.7% of patients were highly satisfied with the treatment. No serious complication related to IGB was observed.

CONCLUSION

IGB is a safe and effective device that achieves moderate weight loss in obese ethnic Chinese patients.

摘要

背景

我们评估了胃内球囊（IGB）治疗香港华裔肥胖患者的有效性和安全性。

方法

自2004年11月起，15名中国患者（10名女性；中位年龄40岁（范围21 - 58岁））在10个月内完成了IGB治疗。基线体重（BW）中位数和BMI分别为100.1（范围78.5 - 170.3）kg和39.4（范围29.6 - 56.9）kg/m²。80%的患者存在与肥胖相关的并存疾病。采用了Bioenterics胃内球囊（BIB），所有放置和取出操作均在静脉清醒镇静下通过内镜进行。球囊放置后，采用多学科方法规定了限制均衡饮食（约1200千卡/天）和每周150分钟的中等强度运动。前瞻性收集并评估结果指标。

结果

中位手术时间为25（范围19 - 45）分钟，中位住院时间为2（范围1 - 6）天。IGB治疗后，BW和BMI中位数下降分别为15.3（范围5.3 - 30.9）kg和5.6（范围1.9 - 12.5）kg/m²。中位腰围（WC）下降9（范围4 - 23）cm，66.7%的患者对治疗高度满意。未观察到与IGB相关的严重并发症。