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[新辅助放化疗及腹腔镜辅助腹会阴联合切除术治疗慢性肛瘘黏液腺癌]

[Mucinous adenocarcinoma on chronic perianal fistula treated by neoadjuvant chemoradiotherapy and laparoscopy-assisted abdominoperineal amputation].

作者信息

Ibáñez Javier, Erro José M, Aranda Francisca, Almendral María Luz, Valenti Carla, Echenique-Elizondo Miguel

机构信息

Servicio de Cirugía General y Aparato Digestivo, Hospital de Zumárraga, Zumárraga, Guipúzcoa, País Vasco, Spain.

出版信息

Cir Esp. 2006 Mar;79(3):184-5. doi: 10.1016/s0009-739x(06)70847-8.

DOI:10.1016/s0009-739x(06)70847-8
PMID:16545286
Abstract

We present a male patient with a perianal fistula of 30 years' duration that had been treated on several occasions. The patient presented with mucoid anal adenocarcinoma. He was treated with preoperative neoadjuvant chemotherapy (5-FU and leucovorin) and external radiation therapy plus laparoscopy-assisted abdominoperineal amputation. Mucoid adenocarcinoma on chronic perianal fistula is an infrequent process. Late diagnosis is associated with a poor prognosis.

摘要

我们报告一名患有30年肛周瘘管的男性患者,该瘘管已接受过多次治疗。患者出现黏液性肛管腺癌。他接受了术前新辅助化疗(5-氟尿嘧啶和亚叶酸钙)、外照射放疗以及腹腔镜辅助腹会阴联合切除术。慢性肛周瘘管并发黏液性腺癌是一种罕见的情况。诊断延迟与预后不良相关。

相似文献

1
[Mucinous adenocarcinoma on chronic perianal fistula treated by neoadjuvant chemoradiotherapy and laparoscopy-assisted abdominoperineal amputation].[新辅助放化疗及腹腔镜辅助腹会阴联合切除术治疗慢性肛瘘黏液腺癌]
Cir Esp. 2006 Mar;79(3):184-5. doi: 10.1016/s0009-739x(06)70847-8.
2
Mucinous adenocarcinoma on chronic perianal fistula treated by neoadjuvant QT-RT neoadyuvante and laparoscopic abdomino-perineal resection.新辅助调强放疗联合腹腔镜腹会阴切除术治疗慢性肛瘘伴黏液腺癌
Rev Esp Enferm Dig. 2006 Apr;98(4):310-2. doi: 10.4321/s1130-01082006000400012.
3
[Laparoscopic abdominoperineal resection after preoperative chemoradiotherapy for advanced carcinoma associated with anal fistula].
Gan To Kagaku Ryoho. 2014 Nov;41(12):1875-7.
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Mucinous adenocarcinoma on perianal fistula. A rising entity?肛周瘘管的黏液腺癌。一种新出现的实体瘤?
Clin Transl Oncol. 2018 May;20(5):666-669. doi: 10.1007/s12094-017-1750-y. Epub 2017 Sep 19.
5
Mucinous adenocarcinoma in chronic anorectal fistula.慢性肛肠瘘中的黏液腺癌。
Chir Ital. 1999 Sep-Oct;51(5):413-6.
6
Mucinous adenocarcinoma arising from chronic perianal fistula mimicking horseshoe abscess.起源于慢性肛瘘的黏液腺癌,形似马蹄形脓肿。
BMJ Case Rep. 2018 Apr 5;2018:bcr-2017-223063. doi: 10.1136/bcr-2017-223063.
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[A Case of Carcinoma Associated with an Anal Fistula Repaired Using a Hatchet Flap after Neoadjuvant Chemoradiotherapy].
Gan To Kagaku Ryoho. 2016 Nov;43(12):1650-1652.
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Perianal mucinous adenocarcinoma and fistula-in-ano.肛周黏液腺癌与肛瘘
Mil Med. 1986 Oct;151(10):543-6.
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[Perianal colloid adenocarcinoma. Apropos of a case].
J Chir (Paris). 1988 Apr;125(4):276-8.
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[Mucoid carcinoma of the anus and perianal fistula: a clinical case and review of the literature].
G Chir. 1989 Apr;10(4):170-2.

引用本文的文献

1
Surgical management of mucinous adenocarcinoma arising in perianal fistula: A case series.肛周瘘管黏液腺癌的手术治疗:病例系列
Surg Open Sci. 2025 Apr 17;26:1-5. doi: 10.1016/j.sopen.2025.04.005. eCollection 2025 Jun.
2
Synchronous anal mucinous adenocarcinoma and anal tuberculosis presenting as chronic anal fistula: Challenging management.同步性肛管黏液腺癌与肛管结核表现为慢性肛瘘:具有挑战性的管理。
Arch Clin Cases. 2023 Jun 7;10(2):74-77. doi: 10.22551/2023.39.1002.10245. eCollection 2023.
3
Adjuvant chemoradiotherapy does not improve outcomes in patients with fistula-associated anal adenocarcinoma undergoing abdominoperineal resection.
辅助放化疗并不能改善接受腹会阴联合切除术的瘘管相关性肛管腺癌患者的预后。
Front Oncol. 2022 Nov 9;12:1061513. doi: 10.3389/fonc.2022.1061513. eCollection 2022.
4
Mucinous adenocarcinoma of perianal region: an uncommon disease treated with neo-adjuvant chemo-radiation.肛周黏液腺癌:一种采用新辅助放化疗治疗的罕见疾病。
Transl Gastroenterol Hepatol. 2016 Jun 21;1:52. doi: 10.21037/tgh.2016.06.03. eCollection 2016.
5
Mucinous adenocarcinoma arising in chronic perianal fistula: good results with neoadjuvant chemoradiotherapy followed by surgery.慢性肛瘘中发生的黏液腺癌:新辅助放化疗后手术取得良好效果。
Case Rep Surg. 2014;2014:386150. doi: 10.1155/2014/386150. Epub 2014 Nov 18.