Borovskikh N A, Andrushchuk Iu V, Levshankov K A
Vestn Khir Im I I Grek. 1991 Mar;146(3):92-5.
The influence of the method of anesthesia on the degree of changes of homeostasis after reconstructive operations on the abdominal aorta was studied in 95 patients. Under conditions of artificial ventilation of lungs fluothane narcosis was used in 9 patients, either narcosis--in 15 patients, combined neuroleptanalgesia--in 35 patients, epidural anesthesia with spontaneous respiration with atmospheric air--in 36 patients. It was shown that fluothane narcosis and neuroleptanalgesia brought about considerable changes of homeostasis and was followed by reliably greater amount of complications and lethal issues. A conclusion was made that general anesthetics, hyperoxia and artificial ventilation of lungs aggravate postischemic tissue alterations, inhibit hemopoiesis and functions of parenchymatous organs and provoke severe postoperative complications and lethal issues.
对95例腹主动脉重建手术后麻醉方法对体内稳态变化程度的影响进行了研究。在肺人工通气条件下，9例患者使用氟烷麻醉，15例患者使用单纯麻醉，35例患者使用联合神经安定镇痛，36例患者使用硬膜外麻醉并自主呼吸空气。结果表明，氟烷麻醉和神经安定镇痛会导致体内稳态发生显著变化，随后出现的并发症和致死病例数量明显更多。得出的结论是，全身麻醉、高氧和肺人工通气会加重缺血后组织改变，抑制造血和实质器官功能，并引发严重的术后并发症和致死病例。
