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[Feasibility and safety of long-term AAI(R) pacing in isolated sinus node syndrome].

作者信息

Körber T, Voss W, Ismer B, Weber F, Nienaber C A, von Knorre G H

机构信息

Abteilung für Kardiologie, Klinik für Innere Medizin der Universität, Postfach 100888, 18055 Rostock.

出版信息

Herzschrittmacherther Elektrophysiol. 2006 Mar;17(1):19-25. doi: 10.1007/s00399-006-0503-3.

DOI:10.1007/s00399-006-0503-3
PMID:16547656
Abstract

Recent investigations prove that AAI(R) pacing is the "ideal" stimulation mode in isolated sick sinus syndrome. Nevertheless, in Germany this bradycardia is treated by AAI(R) pacemakers in less than 4% of cases compared to 25% in other countries. In our institution treatment of patients with isolated sick sinus syndrome is uniform and corresponds to the actual guidelines since the early 1990s; therefore the aim of our study was to analyze feasibility and safety of AAI(R) pacing in a retrospective study. Between 1998 and 2000, 52 of 165 patients (31.5%) with isolated sick sinus syndrome were treated by an AAI(R) pacemaker. The median follow-up duration was 51.5 months (minimal: 36 months). 6 patients died, in all cases unrelated to the stimulation mode. Three patients required reoperations, however, in only one case due to second degree AV block with the need for upgrading to DDD stimulation. Thus, the yearly incidence of this specific complication in the AAI(R) cohort is 0.64%.In conclusion, permanent atrial stimulation in isolated sick sinus syndrome is feasible in a quarter of all cases. It is safe if performed corresponding to actual guidelines. Additionally, single lead AAI(R) pacing is a cost-effective therapy and the only stimulation mode which, today, reliably prevents unnecessary right ventricular stimulation. If, on the other hand, algorithms providing automatic mode switching from AAI to DDD and vice versa are implemented reliably into all dual chamber pacemakers, single chamber atrial pacing will no longer be a subject for discussion.

摘要

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2
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引用本文的文献

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[Maintenance of AAI(R) mode at the time of generator replacement].[更换发生器时AAI(R)模式的维持]
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本文引用的文献

1
[Guidelines for heart pacemaker therapy].[心脏起搏器治疗指南]
Z Kardiol. 2005 Oct;94(10):704-20. doi: 10.1007/s00392-005-0269-3.
2
[2003 yearly report of the German heart pacemaker registry].[德国心脏起搏器注册中心2003年年报]
Herzschrittmacherther Elektrophysiol. 2005 Sep;16(3):193-218. doi: 10.1007/s00399-005-0460-2.
3
Pacemaker selection - the changing definition of physiologic pacing.起搏器的选择——生理性起搏定义的演变
N Engl J Med. 2005 Jul 14;353(2):202-4. doi: 10.1056/NEJMe058125.
4
Atrial pacing should be used more frequently in sinus node disease.心房起搏在窦房结疾病中应更频繁地使用。
Pacing Clin Electrophysiol. 2005 Apr;28(4):291-4. doi: 10.1111/j.1540-8159.2005.08672.x.
5
Long-term clinical performance of AAI pacing in patients with sick sinus syndrome: a comparison with dual-chamber pacing.病态窦房结综合征患者AAI起搏的长期临床疗效:与双腔起搏的比较。
Europace. 2004 Sep;6(5):444-50. doi: 10.1016/j.eupc.2004.05.003.
6
Evidence base for pacemaker mode selection: from physiology to randomized trials.起搏器模式选择的循证依据:从生理学到随机试验
Circulation. 2004 Feb 3;109(4):443-51. doi: 10.1161/01.CIR.0000115642.05037.0E.
7
Canadian Trial of Physiological Pacing: Effects of physiological pacing during long-term follow-up.加拿大生理性起搏试验:长期随访期间生理性起搏的效果。
Circulation. 2004 Jan 27;109(3):357-62. doi: 10.1161/01.CIR.0000109490.72104.EE. Epub 2004 Jan 5.
8
Adverse effects of ventricular desynchronization induced by long-term right ventricular pacing.长期右心室起搏所致心室失同步的不良反应。
J Am Coll Cardiol. 2003 Aug 20;42(4):624-6. doi: 10.1016/s0735-1097(03)00769-1.
9
A randomized comparison of atrial and dual-chamber pacing in 177 consecutive patients with sick sinus syndrome: echocardiographic and clinical outcome.177例连续病态窦房结综合征患者心房起搏与双腔起搏的随机对照研究:超声心动图及临床结果
J Am Coll Cardiol. 2003 Aug 20;42(4):614-23. doi: 10.1016/s0735-1097(03)00757-5.
10
Adverse effect of ventricular pacing on heart failure and atrial fibrillation among patients with normal baseline QRS duration in a clinical trial of pacemaker therapy for sinus node dysfunction.在一项针对窦房结功能障碍的起搏器治疗临床试验中,心室起搏对基线QRS时限正常患者的心力衰竭和心房颤动的不良影响。
Circulation. 2003 Jun 17;107(23):2932-7. doi: 10.1161/01.CIR.0000072769.17295.B1. Epub 2003 Jun 2.