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以呕血为主要症状的胃癌患者的临床研究

Clinical study of gastric cancer patients with complaint of hematemesis.

作者信息

Ajisaka Hideyuki, Miwa Koichi

机构信息

Department of Emergency, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

出版信息

Int Surg. 2005 Sep-Oct;90(4):198-201.

Abstract

Eighteen gastric cancer patients with complaint of hematemesis, who underwent early endoscopic treatment for hemorrhage and received standby oncologic treatment after recovery, were retrospectively compared with 661 gastric cancer patients without complaint of hematemesis. Patients with hematemesis had a statistically high rate of type 2 gastric cancers. Stage I in patients with hematemesis was significantly less frequent than in patients without. Standby gastrectomy after early endoscopic treatment was performed on 17 (94.4%) of the patients with complaint of hematemesis. The resected specimens showed a significant association of hematemesis with serosal invasion, node metastases, and vascular invasion. However, there was no significant association of hematemesis and postoperative complications or prognosis. Our findings suggest that prognosis of gastric cancer patients with hematemesis has improved with the development of endoscopic diagnosis and treatment. For such patients, it is very important to decide on an oncologic treatment plan after endoscopic treatment and accurate assessment of the cancer stage.

摘要

18例因呕血而接受早期内镜下止血治疗并在恢复后接受后续肿瘤治疗的胃癌患者,与661例无呕血症状的胃癌患者进行回顾性比较。呕血患者的2型胃癌发生率在统计学上较高。呕血患者的I期比例明显低于无呕血患者。17例(94.4%)有呕血症状的患者在早期内镜治疗后接受了备用胃切除术。切除标本显示呕血与浆膜侵犯、淋巴结转移和血管侵犯之间存在显著关联。然而,呕血与术后并发症或预后之间无显著关联。我们的研究结果表明,随着内镜诊断和治疗的发展,呕血的胃癌患者的预后有所改善。对于此类患者,在内镜治疗后决定肿瘤治疗方案并准确评估癌症分期非常重要。

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