Calabrese Leonard
Section of Clinical Immunology, Department of Rheumatic and Immunologic Disease, The Cleveland Clinic Foundation, OH 44195, USA.
Cleve Clin J Med. 2006 Mar;73(3):251-6. doi: 10.3949/ccjm.73.3.251.
Tumor necrosis factor (TNF) inhibitors have proven highly effective against a number of autoimmune diseases but have been disappointing in treating others. An increase in the risk of Mycobacterium tuberculosis and other opportunistic infections has been noted in patients treated with these agents. If we use these drugs, we need to weigh their beneficial and adverse effects.
肿瘤坏死因子（TNF）抑制剂已被证明对多种自身免疫性疾病非常有效，但在治疗其他疾病方面却不尽人意。使用这些药物的患者中，已注意到结核分枝杆菌和其他机会性感染的风险增加。如果我们使用这些药物，就需要权衡它们的利弊。
