Hofer C K, Ganter M T, Matter-Ensner S, Furrer L, Klaghofer R, Genoni M, Zollinger A
Consultant, Institute of Anaesthesiology and Intensive Care Medicine, Triemli City Hospital Zurich, Birmensdorferstr. 497, 8063 Zurich, Switzerland.
Anaesthesia. 2006 Apr;61(4):316-21. doi: 10.1111/j.1365-2044.2006.04537.x.
The new Volumetric Ejection Fraction monitoring system (VoLEF), when combined with the Pulse Contour Cardiac Output monitoring system (PiCCO) system, allows measurement of left and right heart end-diastolic volumes by thermodilution. The aim of this study was to evaluate whether the left heart end-diastolic volume index determined by the VoLEF system (LHEDI) better reflects left ventricular end-diastolic area index (LVEDAI) measured by transoesophageal echocardiography than does global end-diastolic volume index (GEDI) measured by the PiCCO system alone. Following induction of anaesthesia, PiCCO, VoLEF and transoesophageal echocardiography measurements were performed before and after a fluid challenge in 20 patients scheduled for elective cardiac surgery. Both left ventricular end-diastolic area index and global end-diastolic volume index, but not left heart end-diastolic volume index, significantly increased after fluid administration. Mean bias +/- 2 SD for DeltaLHEDI-DeltaLVEDAI was -2.2 +/- 32.0% and for DeltaGEDI-DeltaLVEDAI -0.6 +/- 16.8%. In contrast to global end-diastolic volume index, the use of left heart end-diastolic volume index determined by the VoLEF system cannot be recommended as an estimate of left ventricular preload.
新型容量射血分数监测系统（VoLEF）与脉搏轮廓心输出量监测系统（PiCCO）联合使用时，可通过热稀释法测量左、右心舒张末期容积。本研究的目的是评估VoLEF系统测定的左心舒张末期容积指数（LHEDI）是否比单独使用PiCCO系统测定的全心舒张末期容积指数（GEDI）能更好地反映经食管超声心动图测量的左心室舒张末期面积指数（LVEDAI）。对20例择期心脏手术患者在麻醉诱导后、液体负荷前后进行PiCCO、VoLEF和经食管超声心动图测量。液体输注后，左心室舒张末期面积指数和全心舒张末期容积指数均显著增加，但左心舒张末期容积指数未增加。DeltaLHEDI-DeltaLVEDAI的平均偏差±2SD为-2.2±32.0%，DeltaGEDI-DeltaLVEDAI为-0.6±16.8%。与全心舒张末期容积指数不同，不推荐使用VoLEF系统测定的左心舒张末期容积指数来评估左心室前负荷。
