Woolley P D, Lacey H B, Helsen K
Department of Genitourinary Medicine, Royal Hallamshire Hospital, Sheffield, UK.
Int J STD AIDS. 1991 Jul-Aug;2(4):287-8. doi: 10.1177/095646249100200413.
In a prospective study to identify the viral type isolated from women undergoing screening for herpes simplex virus (HSV) during pregnancy using fluoroscine-labelled monoclonal antibodies to HSV-1 and HSV-2, HSV-2 was more likely to be isolated during the third trimester and was the only viral type isolated at term. As the severity of neonatal central nervous system disease is greater with HSV-2 than HSV-1 we recommended that all women with a history of genital herpes should be screened during pregnancy.
在一项前瞻性研究中，使用荧光标记的抗单纯疱疹病毒1型（HSV-1）和抗单纯疱疹病毒2型（HSV-2）单克隆抗体，对孕期接受单纯疱疹病毒筛查的女性所分离出的病毒类型进行鉴定。结果显示，HSV-2更有可能在妊娠晚期被分离出来，并且是足月时唯一分离出的病毒类型。由于HSV-2导致的新生儿中枢神经系统疾病比HSV-1更严重，我们建议所有有生殖器疱疹病史的女性在孕期都应接受筛查。
