Johnsson M, Richardson C F, Sallis J D, Nancollas G H
Department of Chemistry, SUNY, Buffalo, New York.
Calcif Tissue Int. 1991 Aug;49(2):134-7. doi: 10.1007/BF02565136.
The adsorption of citrate and phosphocitrate ions by hydroxyapatite (HAP) surfaces and their influence on the constant composition growth kinetics of HAP have been investigated. Phosphocitrate was strongly adsorbed to HAP and inhibited crystal growth. When HAP surfaces containing preadsorbed citrate were exposed to phosphocitrate, the uptake of the latter markedly increased. The two additives behaved synergistically in their HAP crystal growth inhibition.
研究了柠檬酸根离子和磷酸柠檬酸根离子在羟基磷灰石（HAP）表面的吸附及其对HAP恒组成生长动力学的影响。磷酸柠檬酸根被强烈吸附到HAP上并抑制晶体生长。当含有预吸附柠檬酸的HAP表面暴露于磷酸柠檬酸根时，后者的吸收显著增加。这两种添加剂在抑制HAP晶体生长方面表现出协同作用。
