Reinberg Y, Manivel J C, Zhang G, Reddy P K
Urology Section, Department of Veterans Affairs Medical Center, Minneapolis, MN 55417.
Cancer. 1991 Sep 1;68(5):1082-5. doi: 10.1002/1097-0142(19910901)68:5<1082::aid-cncr2820680529>3.0.co;2-x.
Patients with a germ cell tumor (GCT) in one testicle are prone to develop cancer in the contralateral testicle. Metachronous development of a GCT in the remaining testicle occurs in 3% of patients. The synchronous development of bilateral GCT occurs in 0.5% of patients. Bilateral testicular neoplasms are almost always identical histologically. Only five cases of synchronous bilateral GCT of different histologic types have been reported in the literature. The authors report the sixth case of this uncommon phenomenon and discuss its clinical and pathogenetic implications.
一侧睾丸患有生殖细胞肿瘤(GCT)的患者容易在对侧睾丸发生癌症。其余睾丸中GCT的异时性发生在3%的患者中。双侧GCT的同时性发生在0.5%的患者中。双侧睾丸肿瘤在组织学上几乎总是相同的。文献中仅报道了5例不同组织学类型的同时性双侧GCT病例。作者报告了这一罕见现象的第6例,并讨论了其临床和发病机制意义。