中性粒细胞减少性小肠结肠炎的超声征象。
Sonographic signs of neutropenic enterocolitis.
作者信息
Dietrich Christoph-F, Hermann Stella, Klein Stefan, Braden Barbara
机构信息
2nd Department of Internal Medicine, Caritas Hospital Bad Mergentheim, Bad Mergentheim, Germany.
出版信息
World J Gastroenterol. 2006 Mar 7;12(9):1397-402. doi: 10.3748/wjg.v12.i9.1397.
Abstract
AIM
To investigate the sonographic features at time of diagnosis and follow-up in patients with neutropenic enterocolitis.
METHODS
The sonographic findings in 14 patients with neutropenic enterocolitis were described and evaluated regarding symptoms and clinical outcome.
RESULTS
In all patients with neutropenic enterocolitis, the ileocoecal region was involved with wall thickening >10 mm. A transmural inflammatory pattern, hypervascularity of the thickened bowel wall and free abdominal fluid were the common findings. The sonographically revealed thickness of the bowel wall was associated with lethal outcome (P<0.03). In the 11 surviving patients,the improvement of clinical symptoms was accompanied by progressive reduction of intestinal wall thickness.
CONCLUSION
High-end sonography of the bowel is a helpful tool for diagnosis,assessment of prognosis and follow-up of patients with neutropenic enterocolitis.The ultrasonographically revealed bowel thickness reflects the severity and the course of the disease, and seems to be predictive for the clinical outcome.
摘要
目的
探讨中性粒细胞减少性小肠结肠炎患者诊断及随访时的超声特征。
方法
描述并评估14例中性粒细胞减少性小肠结肠炎患者的超声检查结果，并分析其症状及临床转归。
结果
所有中性粒细胞减少性小肠结肠炎患者的回盲部均受累，肠壁增厚>10 mm。常见表现为透壁性炎症模式、增厚肠壁血管增多及腹腔游离液体。超声显示的肠壁厚度与致死性结局相关（P<0.03）。在11例存活患者中，临床症状的改善伴随着肠壁厚度的逐渐减小。
结论
肠道的高端超声检查是诊断、评估中性粒细胞减少性小肠结肠炎患者预后及进行随访的有用工具。超声显示的肠壁厚度反映了疾病的严重程度及病程，似乎对临床结局具有预测作用。
相似文献
1
Sonographic signs of neutropenic enterocolitis.中性粒细胞减少性小肠结肠炎的超声征象。
World J Gastroenterol. 2006 Mar 7;12(9):1397-402. doi: 10.3748/wjg.v12.i9.1397.
2
Neutropenic enterocolitis in patients with acute leukemia: prognostic significance of bowel wall thickening detected by ultrasonography.急性白血病患者的中性粒细胞减少性小肠结肠炎：超声检测肠壁增厚的预后意义
J Clin Oncol. 2001 Feb 1;19(3):756-61. doi: 10.1200/JCO.2001.19.3.756.
3
Neutropenic enterocolitis in children and young adults with cancer: prognostic value of clinical and image findings.儿童和青年癌症患者的中性粒细胞减少性小肠结肠炎：临床和影像表现的预后价值
Pediatr Hematol Oncol. 2010 Sep;27(6):462-70. doi: 10.3109/08880018.2010.489934.
4
Neutropenic enterocolitis.中性粒细胞减少性小肠结肠炎
Surg Infect (Larchmt). 2009 Jun;10(3):307-14. doi: 10.1089/sur.2008.061.
5
ED presentation of neutropenic enterocolitis in adult patients with acute leukemia.成人急性白血病患者中性粒细胞减少性小肠结肠炎的急诊表现。
Am J Emerg Med. 2004 Jul;22(4):276-9. doi: 10.1016/j.ajem.2004.02.014.
6
Neutropenic Enterocolitis: New Insights Into a Deadly Entity.中性粒细胞减少性小肠结肠炎：对一种致命疾病的新认识
Am J Surg Pathol. 2015 Dec;39(12):1635-42. doi: 10.1097/PAS.0000000000000517.
7
Fanconi anemia complicated by neutropenic enterocolitis.范可尼贫血合并中性粒细胞减少性小肠结肠炎。
Tunis Med. 2008 Nov;86(11):1011-3.
8
[Isolated edematous swelling of Bauhin's valve -- sonographically suspected diagnosis of a rare ileocoecal disease].[鲍欣氏瓣孤立性水肿性肿胀——超声检查疑似诊断一种罕见的回盲部疾病]
Ultraschall Med. 2005 Oct;26(5):415-9. doi: 10.1055/s-2005-858029.
9
[Clinical and microbiological characteristics of neutropenic enterocolitis in adults with blood cancer in the National Cancer Institute of Bogota D.C. (Colombia)].[哥伦比亚波哥大特区国立癌症研究所成年血癌患者中性粒细胞减少性小肠结肠炎的临床和微生物学特征]
Enferm Infecc Microbiol Clin. 2004 Oct;22(8):462-6. doi: 10.1157/13066853.
10
[Neutropenic enterocolitis in adult patients with acute leukemia or stem cell transplant recipients: study of 7 cases].[成人急性白血病患者或干细胞移植受者的中性粒细胞减少性小肠结肠炎：7例研究]
Med Clin (Barc). 2007 Nov 10;129(17):660-3. doi: 10.1157/13112098.
引用本文的文献
1
Investigating neutropenic enterocolitis: a systematic review of case reports and clinical insights.中性粒细胞减少性小肠结肠炎的研究：病例报告及临床见解的系统评价
BMC Gastroenterol. 2025 Jan 13;25(1):17. doi: 10.1186/s12876-025-03601-y.
2
Impact of different chemotherapy regimens on intestinal mucosal injury assessed with bedside ultrasound: a study in 213 AML patients.床旁超声评估不同化疗方案对肠道黏膜损伤的影响：213例急性髓系白血病患者的研究
Front Oncol. 2023 Nov 1;13:1272072. doi: 10.3389/fonc.2023.1272072. eCollection 2023.
3
Early Diagnosis of Neutropenic Enterocolitis by Bedside Ultrasound in Hematological Malignancies: A Prospective Study.床边超声对血液系统恶性肿瘤中性粒细胞减少性小肠结肠炎的早期诊断：一项前瞻性研究
J Clin Med. 2021 Sep 21;10(18):4277. doi: 10.3390/jcm10184277.
4
Neutropenic enterocolitis in pediatric leukemia patients treated with intensive chemotherapy in Upper Egypt.埃及上埃及地区接受强化化疗的小儿白血病患者中的中性粒细胞减少性小肠结肠炎。
Pediatr Investig. 2020 Mar 17;4(1):5-10. doi: 10.1002/ped4.12174. eCollection 2020 Mar.
5
Chemotherapy-associated neutropenic enterocolitis of the transverse colon post right hemicolectomy.右半结肠切除术后横结肠化疗相关性中性粒细胞减少性小肠结肠炎
Oxf Med Case Reports. 2019 Dec 19;2019(11):omz140. doi: 10.1093/omcr/omz140. eCollection 2019 Nov.
6
Role of contrast-enhanced ultrasound in evaluation of the bowel.对比增强超声在肠道评估中的作用。
Abdom Radiol (NY). 2018 Apr;43(4):918-933. doi: 10.1007/s00261-017-1399-6.
7
Ultrasonography-driven combination antibiotic therapy with tigecycline significantly increases survival among patients with neutropenic enterocolitis following cytarabine-containing chemotherapy for the remission induction of acute myeloid leukemia.超声引导下替加环素联合抗生素治疗显著提高了急性髓系白血病诱导缓解含阿糖胞苷化疗后中性粒细胞减少性小肠结肠炎患者的生存率。
Cancer Med. 2017 Jul;6(7):1500-1511. doi: 10.1002/cam4.1063. Epub 2017 May 26.
8
Ultrasound findings guided a successful hemicolectomy in a leukemic patient with neutropenic enterocolitis.超声检查结果指导了一名患有中性粒细胞减少性小肠结肠炎的白血病患者成功进行了半结肠切除术。
J Ultrasound. 2008 Sep;11(3):97-101. doi: 10.1016/j.jus.2008.05.001. Epub 2008 Jul 3.
9
Diarrhea in neutropenic children with cancer: An Egyptian center experience, with emphasis on neutropenic enterocolitis.癌症中性粒细胞减少儿童的腹泻：一家埃及中心的经验，重点关注中性粒细胞减少性小肠结肠炎。
Indian J Med Paediatr Oncol. 2012 Apr;33(2):95-101. doi: 10.4103/0971-5851.99742.
10
Neutropenic enterocolitis: current issues in diagnosis and management.中性粒细胞减少性肠炎：诊断与治疗的当前问题。
Curr Infect Dis Rep. 2007 Mar;9(2):116-20. doi: 10.1007/s11908-007-0006-3.
本文引用的文献
1
Neutropenic enterocolitis in adults: systematic analysis of evidence quality.成人中性粒细胞减少性小肠结肠炎：证据质量的系统分析
Eur J Haematol. 2005 Jul;75(1):1-13. doi: 10.1111/j.1600-0609.2005.00442.x.
2
Neutropenic enterocolitis in lung cancer: a report of two cases and a review of the literature.肺癌患者的中性粒细胞减少性小肠结肠炎：两例报告并文献复习
Intern Med. 2005 May;44(5):467-70. doi: 10.2169/internalmedicine.44.467.
3
ED presentation of neutropenic enterocolitis in adult patients with acute leukemia.成人急性白血病患者中性粒细胞减少性小肠结肠炎的急诊表现。
Am J Emerg Med. 2004 Jul;22(4):276-9. doi: 10.1016/j.ajem.2004.02.014.
4
Neutropenic enterocolitis in acute leukemia: diagnostic and therapeutic dilemma.急性白血病中的中性粒细胞减少性小肠结肠炎：诊断与治疗困境
Ann Hematol. 2004 Mar;83(3):195-7. doi: 10.1007/s00277-003-0755-5. Epub 2003 Oct 3.
5
Neutropenic enterocolitis: a serious complication during the treatment of acute leukemias.中性粒细胞减少性小肠结肠炎：急性白血病治疗期间的一种严重并发症。
Ann Hematol. 2004 Aug;83(8):522-6. doi: 10.1007/s00277-003-0815-x. Epub 2003 Dec 5.
6
Fatal Bacillus cereus sepsis following resolving neutropenic enterocolitis during the treatment of acute leukemia.急性白血病治疗期间中性粒细胞减少性小肠结肠炎缓解后发生的致死性蜡样芽孢杆菌败血症
Am J Hematol. 2003 Mar;72(3):204-8. doi: 10.1002/ajh.10272.
7
Gastrointestinal complications in the neutropenic patient: characterization and differentiation with abdominal CT.中性粒细胞减少患者的胃肠道并发症：腹部CT的特征与鉴别
Radiology. 2003 Mar;226(3):668-74. doi: 10.1148/radiol.2263011932. Epub 2003 Jan 24.
8
The value of routinely performed ultrasonography in patients with Crohn disease.常规超声检查在克罗恩病患者中的价值。
Scand J Gastroenterol. 2002 Oct;37(10):1178-83. doi: 10.1080/003655202760373399.
9
Neutropenic enterocolitis.中性粒细胞减少性小肠结肠炎
Curr Gastroenterol Rep. 2002 Aug;4(4):297-301. doi: 10.1007/s11894-002-0079-y.
10
A new approach to evaluating intestinal acute graft-versus-host disease by transabdominal sonography and colour Doppler imaging.一种通过经腹超声和彩色多普勒成像评估肠道急性移植物抗宿主病的新方法。
Br J Haematol. 2001 Dec;115(4):929-34. doi: 10.1046/j.1365-2141.2001.03221.x.
Zotero 插件