Miller S, Hamza S, Bray E H, Lester F, Nada K, Gibson R, Fathalla M, Mourad M, Fathy A, Turan J M, Dau K Q, Nasshar I, Elshair I, Hensleigh P
Women's Global Health Imperative, Department of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco 94105, USA.
BJOG. 2006 Apr;113(4):424-9. doi: 10.1111/j.1471-0528.2006.00873.x.
To compare the effect of non-pneumatic anti-shock garment (NASG) on blood loss from obstetric haemorrhage with standard management of obstetric haemorrhage.
Observational study of consecutive obstetric haemorrhage cases before and after introduction of the NASG.
Four tertiary care maternity facilities in Egypt.
The sample consisted of women with obstetric haemorrhage and signs of shock and the entry criteria were: >750 mL of blood loss and either pulse of >100 beats per minute or systolic blood pressure of <100 mmHg. A total of 158 women were in the preintervention group and 206 in the postintervention group.
All the women with haemorrhage meeting the eligibility criteria were treated according to the standard protocol for 4 months (May-August 2004); blood loss was measured and recorded. The NASG was then introduced, and all the women meeting the eligibility criteria were treated according to the standard haemorrhage protocol plus the NASG for 4 months (September-December 2004).
Measured blood loss collected in a closed-end, graduated, plastic, under buttocks collection drape.
Median measured blood loss in the drape following study entry was 50% lower in those treated with the NASG (250 versus 500 mL, P < 0.001). There was also a non-statistically significant decrease in morbidity and mortality.
This is the first comparative study of the NASG with a standard obstetric haemorrhage treatment protocol. The NASG shows promise for management of obstetric haemorrhage, particularly in lower resource settings. Larger studies will be needed to determine if the NASG contributes to statistically significant decreases in morbidity and mortality.
比较非充气抗休克服(NASG)与产科出血标准处理方法对产科出血失血的影响。
对引入NASG前后连续的产科出血病例进行观察性研究。
埃及的四家三级护理产科机构。
样本包括产科出血且有休克体征的女性,入选标准为:失血>750毫升,且心率>100次/分钟或收缩压<100毫米汞柱。干预前组共有158名女性,干预后组有206名。
所有符合入选标准的出血女性按照标准方案治疗4个月(2004年5月至8月);测量并记录失血量。然后引入NASG,所有符合入选标准的女性按照标准出血方案加NASG治疗4个月(2004年9月至12月)。
在臀部下方的封闭式、刻度塑料收集单中收集测量的失血量。
研究开始后,接受NASG治疗的患者收集单中测量的失血量中位数降低了50%(250毫升对500毫升,P<0.001)。发病率和死亡率也有非统计学意义的下降。
这是首次将NASG与标准产科出血治疗方案进行比较的研究。NASG在产科出血管理方面显示出前景,尤其是在资源较少的环境中。需要进行更大规模的研究来确定NASG是否能使发病率和死亡率在统计学上显著降低。